Benign adrenal virilization

After puberty, masculinity such as hairiness and amenorrhea are rarely found, and occasionally cause virilization in middle age. This acquired mild adrenal enzyme abnormality is called benign virilization of the adrenal cortex. Adrenogenital syndrome is a congenital adrenal hyperplasia. It is a recessive genetic defect. Due to the inadequate synthesis of certain enzymes in the adrenal cortex, the adrenal glands produce hydrocortisone, and the pituitary Increased secretion of ACTH, resulting in adrenal cortex proliferation and excessive male hormones, masculinizing female genitalia and increasing the amount of 17-ketones in the urine of patients. Congenital defects in certain adrenal enzymes cause abnormal steroid production. Women cause pseudohermaphroditism, and male genitalia are huge. After puberty, masculinity such as hairiness and amenorrhea are rarely found, and occasionally cause virilization in middle age. This acquired mild adrenal enzyme abnormality is known as benign adrenal cortex.

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