Membrane response after trematodes parasites

Parasitic fluke disease (also known as pulmonary fluke disease) is caused by parasitic flukes. There are many types of parasitic flukes, and the main pathogenic species in China are parasitic flukes and parasitic flukes. Humans are suitable hosts and non-suitable hosts for Paragonimus weichii and Paragonimus tenuisi, respectively. After infection of the cysts by humans, Paragonimus tenuis develops into adult worms through larvae, while the development of Paragonimus tenuis remains In the larval stage, the former mainly causes pulmonary parasites and the latter mainly causes subcutaneous parasites. Parasitic fluke disease often involves multiple organs such as the lungs, brain, liver, and skin, with more complex symptoms. Parasite flukes have species and strains that share common and specific antigen components. The use of common antigen components is helpful for the diagnosis of parasite flukes. For example, two kinds of parasite flukes can be used to detect different kinds of colonies. Trematodes; specific antigen components can be used to further identify species or stages. Cross-reaction with schistosomiasis and liver fluke disease occurs when crude antibodies against parasites are used to detect specific antibodies in the serum. This cross-reaction can be reduced or eliminated with different purified antigens. The results of animal experiments showed that suitable host was 10 days after infection. The anti-cysticercus antibody first appeared in the serum, and then the titer gradually increased, reaching a peak from 30 to 80 days, and gradually decreasing and continuing to low levels after 90 days. Antibodies appeared as early as 40 days after infection, reached a peak at 80 days, decreased at 90-100 days, and remained at low levels for a long period of time. In a non-suitable host, anti-cystic cyst antibodies appeared on the 15th day after infection, and the titer continued to increase afterwards, reaching a peak at 80 days, and has remained at a high titer antibody level since then; but the antibody response to adult worms was weak and appeared relatively late. After effective treatment in patients with parasitic flukes, the antibody level tends to increase between 1 and 2 months, and the antibody decreases between 3 and 6 months.

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