Myoglobin is high

Introduction Myoglobin is an oxygen-binding heme protein mainly distributed in myocardium and skeletal muscle tissue. Determination of serum myoglobin myoglobin may be the most sensitive early indicator of acute myocardial infarction (AMI) diagnosis. Increased myoglobin: seen in early acute myocardial infarction, acute muscle injury, muscular dystrophy, muscular atrophy, polymyositis, acute or chronic renal failure, severe congestive heart failure and long-term shock. It can be increased 1.5h after myocardial infarction, but it will return to normal within 1~2d.

Cause

Early acute myocardial infarction, acute muscle injury, muscular dystrophy, muscular atrophy, polymyositis, acute or chronic renal failure, severe congestive heart failure, and long-term shock can cause high myoglobin.

an examination

Related inspection

Serum myoglobinuria

1, urinary myoglobin.

2, blood myoglobin.

Differential diagnosis

1, elevated blood: hypothyroidism, hyperaldosteronism, renal insufficiency, malignant hyperthermia and after strenuous exercise.

2, elevated urine: porphyria, hemoglobinuria, hematuria and so on.

3, blood, urine, myoglobin increased: seen in acute myocardial infarction, angina pectoris, cardiogenic shock, cardiomyopathy, muscle disease (progressive muscular dystrophy, polymyositis, myasthenia gravis).

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