Senile vitiligo
Introduction
Introduction Senile leukoplakia, also known as senile white spot disease, is an age-related skin pigmentation phenomenon, which is more common in middle-aged and older people over 45 years old. It is caused by the degeneration and aging of melanocytes in the skin due to the increase of age. Idiopathic punctate leukoplakia, also known as idiopathic pharyngeal hypopigmentation, is associated with human endocrine and skin aging degradation. Many scholars refer to idiopathic leukoplakia as senile leukoplakia.
Cause
Cause
Senile leukoplakia is mostly caused by local skin melanocyte degeneration, aging, decreased tyrosinase activity, and decreased light, endocrine, and skin aging. Patients are often accompanied by other senile changes, such as senile sputum, senile sunspots, senile hemangioma, and gray hair.
Examine
an examination
Related inspection
skin color
Senile leukoplakia, mostly milky white, clear white spot, mostly needle or bean size, white spot on the skin has a slight depression, the incidence is mostly in the trunk, limbs, facial is rare; idiopathic punctate leukoplakia, scattered , point distribution, white spots do not fuse, white spots generally do not occur in the palmar, head and mucosa.
Diagnosis
Differential diagnosis
Idiopathic punctate leukoplakia: skin lesions are mostly milky white or porcelain white spots with a clear boundary, 2~6mm in diameter, round, polygonal or irregular shape, smooth surface; except for palmar, head and mucosa The other parts of the body can be affected; with the increase of age, the incidence of white spots increases, and the incidence rate also increases. Clinically, the multiple manifestations are: white spots appear scattered and point-like distribution, and the white spot is clear and the spots are not fused.
Senile vitiligo: generally does not hurt or itching, the skin white spots are highly consistent with normal skin, and there is no unevenness when touched by hand; when the white spot is first, the white spot boundary is blurred; as time goes by, the age increases, autoimmune Or the mental condition is weakened, the white spot is gradually clear, and the white spot can also explode or spread to any part of the body. It is common in the face, hands, feet, groin, chest, back, armpits, etc. Identification of senile vitiligo.
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