Histamine flush

Introduction Histamine red is the main manifestation of flushing and flushing phobia. Blushing and exythmphobia are caused by temporary vasodilation. Common in patients with obsessive-compulsive neurosis or mental weakness, women are more common. Redness can be associated with redness in other areas. Clinical manifestations of emotional redness, menopause red, carcinoid red, drinking red, histamine red five types. The disease is considered according to the different manifestations of clinical classification.

Cause

(1) Causes of the disease

The mechanism of vasodilation is unclear and can be caused by a variety of factors such as agitation, autonomic dysfunction, endocrine effects, or vasoactive substances acting directly on the dermal blood vessels.

(two) pathogenesis

More due to temporary vasodilation.

an examination

Related inspection

Physical examination of skin diseases

Histamine red, pigmented urticaria or the application of histamine-releasing drugs can cause redness on the skin of the face, neck, chest and limbs for 15 min to 2 h, often accompanied by headache and itchy skin. Increased histamine content in blood and urine.

Differential diagnosis

Differential diagnosis of histamine red:

1. Emotional flush: Some patients may face redness when they are shy, angry, nervous, praised or criticized.

2. Menopausal red: may have paroxysmal flush, short-lived, lasting 5 to 15 minutes. The earliest symptoms are warmth on the face, neck and chest, which in turn turns into flushing, especially when emotional or after a meal. May be associated with other symptoms of menopause.

3. Carcinoid redness: Because carcinoid tissue can produce media such as serotonin and kinin, it can often cause flushing on the face, neck, arms, trunk and calf skin. Emotional changes, overeating, drinking and diarrhea can often be induced. Long-term episodes can cause small blood vessels to dilate, local tissue thickening, and some persistent erythema or skin bruising, and even central necrosis and scar formation. This type can be associated with symptoms of the gastrointestinal tract, respiratory tract, heart and nervous system, and is called carcinoid syndrome in combination with skin symptoms.

4. Drinking redness: Some people can cause redness due to drinking. In addition to facial infrared, neck, chest, back and upper limbs can also be affected, sometimes with urticaria and itching.

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