Atypical reticulocytes

Introduction Reticulocytes are red blood cells that are not yet fully mature. The values in the surrounding blood reflect the function of bone marrow red blood cells, which is important for the diagnosis of blood diseases and the observation of therapeutic response. Reticulocytes are an important indicator of the erythroid hematopoietic function of the bone marrow and the efficacy of anemia and related diseases.

Cause

The cause of heterotypic reticulocytes:

Heteromorphic reticulocytes are more common in malignant granuloma.

an examination

Related inspection

White blood cell count (WBC) general radiography examination Otolaryngology CT examination

Examination and diagnosis of heterogeneous reticulocytes:

1, pathological biopsy presents chronic non-specific granulomatous lesions, if the appearance of heterologous reticulocytes or mitotic phase can diagnose the disease.

2, laboratory tests: white blood cell count is low, erythrocyte sedimentation rate is accelerated; immunoglobulin levels are high, no special discovery of bacteria, fungi and virus culture.

3, CT scan of the tomographic X-ray film.

Differential diagnosis

Mutual identification of confusing symptoms of heterologous reticulocytes:

1, prodromal period: for general cold or sinusitis. Intermittent nasal obstruction with watery or bloody secretions. It can also be manifested as dry intranasal scarring. Local examination is a general inflammatory manifestation, and granulomatous ulcers may occur in the nasal septum. This period lasts for 4-6 weeks.

2, active period: nasal ventilation is not smooth or completely blocked, there are purulent sputum, often smelly. The general condition is acceptable, sweating, poor appetite, often low fever, a few have high fever, and treatment with general antibiotics is ineffective. Local examination showed swelling of the nasal mucosa, erosion and even ulceration, granulation, grayish white necrosis on the surface. More involvement of the inferior turbinate or nasal septum, obvious can cause external expansion of the nose, lesion development can cause perforation of the nasal septum or perforation of the ankle. This period lasts for weeks to months.

3, the end of the period: the patient is weak, cachecosis, partial disfigurement. Nasal mucosa, cartilage, bone and surrounding tissues such as the face, eyelids, forehead and even the skull base can be severely damaged, the eyelids and conjunctiva are swollen, the eyeballs are prominent, and vision is reduced. Finally died of failure, bleeding or complicated meningitis.

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