Abnormal ichthyosis

Introduction Ichthyosis is a common hereditary skin keratosis. It is called ichthyosis, and Chinese medicine is called snake skin. Mainly manifested as dry or rough skin on the extremities or trunk of the extremities, with rhomboid or polygonal scales, the appearance of which is like fish scales or snakeskin. Due to different genetic methods, it can be divided into autosomal dominant ichthyosis, sex. Inherited ichthyosis, congenital ichthyosis-like erythroderma and lamellar ichthyosis.

Cause

The cause of abnormal ichthyosis:

Because of the bloody wind, the wind and evil fight on the skin.

an examination

Related inspection

Fungal histopathology skin fungal microscopy

Examination and diagnosis of abnormal ichthyosis:

1. Hereditary diseases.

2. Four types of skin lesions.

3. Histopathological changes:

(1) Dominant hereditary ichthyosis: moderate epidermal hyperkeratosis with thinning or disappearance of the granular layer.

(2) Sexually connected ichthyosis: excessive keratinization, normal or slightly thick granular layer.

(3) Epidermolytic hyperkeratosis ichthyosis: hyperkeratosis, epidermal cell release, particle degeneration.

Differential diagnosis

Symptoms of abnormal fish scales are easily confused:

1. Dominant ichthyosis vulgaris: (1) 3 months to 5 years old after birth; (2) dry skin, covered with grayish white to light brown diamond or polygonal scales, the periphery is tilted, the center is close to the skin; (3) Mainly distributed on the extremities and back of the extremities.

2. Sexual ichthyosis vulgaris: (1) 3 months after birth, only males; 2) dry and thick skin, overlying large dark brown scales, winter heavy summer light. With age, the damage remains unchanged or even worse; (3) skin lesions are distributed throughout the body, with the heaviest involvement on the head, side, ears, and neck. The flexor side is often involved.

3. Congenital ichthyosis-like erythroderma: (1) There are armor-like multi-layer scales at birth, and there is a rough moist surface after shedding, which may be slack; (2) severe hands and feet are claw-shaped; 3) Autosomal dominant inheritance.

4. Lamellar ichthyosis: (1) After the baby is born, it is tightly wrapped with a layer of extensive cotton-cotton gelatinous membrane. After a few days, the membrane falls off, the skin is extensively flushed, and there are large multi-angled scales with central adhesion and free edges; (2) excessive palmarization, excessive growth of nails and hair; (3) 2/3 patients have valgus valgus.

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