Malabsorption syndrome

Introduction Absorption syndrome is a syndrome caused by malabsorption of small intestine nutrients for various reasons. The absorption of nutrients must be fully digested. Therefore, the generalized malabsorption syndrome includes indigestion and malabsorption, so it is also called "digestive malabsorption syndrome". Many diseases can cause this syndrome, but their clinical manifestations and experimental findings are often similar. Absorption is a variety of nutrients, of which fat absorption disorders are the most characteristic.

Cause

Insufficient secretion of bile or pancreatic juice, excessive bacterial growth in the small intestine, intestinal dyskinesia, intestinal blood circulation or lymphatic circulation disorder, lesions of the small intestine itself, and loss of on-site mucosa.

an examination

Related inspection

Blood routine urine routine routine fat absorption test xylose determination

The number of diarrhea, duration, and the appearance and amount of feces. 80%-97% of patients have diarrhea. The number of stools varies from several times to more than ten times, sometimes with intermittent diarrhea, abdominal pain, and abdominal distension. In addition, attention should be paid to the symptoms of malnutrition such as weight loss, fatigue, hand and foot spasm, paresthesia, stomatitis, corneal dryness, night blindness, and edema. Past examinations and treatments are also helpful in diagnosis. Diarrhea and abdominal pain are the most common symptoms of this disease. Most of the diarrhea is "fat diarrhea". The steatorrhea is characterized by a large amount of stool, light brown or yellow, gray, no shape, bad smell, greasy luster on the surface or foamy, because it contains a lot of fat. Therefore, stool can often float on the surface of the potty. Malnutrition due to insufficient absorption, common weight loss, fatigue and fatigue.

Physical examination found:

Patients may have weight loss, mild tenderness in the abdomen, abnormal sensation in the extremities of the extremities, glossitis or ulceration of the tongue, psoriasis-like coloration, edema, concave nails, muscle tenderness, clubbing (toe) and other signs.

Auxiliary inspection:

Most of them have large cell anemia, serum electrolyte, plasma albumin, cholesterol, and even folic acid, vitamin B12 levels are reduced. The fecal fat was >6g/d, the dextrose absorption test was <3g, and the vitamin B12 absorption test was <8%-10%. When the intestinal flora is dysfunctional, the 14C-glycocholate breath test is positive. Gastrointestinal barium meal pay attention to whether the intestine is dilated, effusion and expectorant deposition "wax tube" sign, endoscopic examination of small intestine villi, wrinkle changes.

Differential diagnosis

Differential diagnosis of malabsorption syndrome:

1, chronic colitis: also often have abdominal pain and diarrhea, but mainly mucus bloody stools, colonic mucosal congestion, edema, ulceration or ulceration.

2, chronic dysentery: diarrhea with pus and bloody stools, a large number of pus blood cells can be seen in the feces, or see dysentery bacilli, stool culture can be seen dysentery bacilli growth.

3, Cronh disease: often have anemia, fever, weakness and other systemic symptoms, colonoscopy see "linear ulcers" or intestinal mucosa "paving stone" changes.

4, intestinal tuberculosis: abdominal pain, diarrhea, pus and blood in the feces and systemic poisoning symptoms, such as weight loss, low fever, or other tuberculosis.

5, intestinal tumor: may have diarrhea, but the old bloody stools, colonoscopy and X-ray barium enema and rectal examination may have positive signs.

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