No beard

Introduction Male long beard is the result of androgen action, long beard is a manifestation of male secondary sexual characteristics, secondary sexual characteristics are caused by male secretion of androgen in the testis after puberty. Before the boy was 11 years old, there were few androgen in the body. The difference in physical signs between men and women was not very large. There was no strict time limit for boys' puberty, usually 10 to 14 years old. The size and shape of the beard is related to the nation and to the family inheritance. No whisker hair and pubic hair are found in Klinefelter syndrome. Also known as congenital testicular hypoplasia or Klinefelter syndrome. The typical karyotype is 47,XXY. The phenotype is characterized by testicular hypoplasia. The slender figure is caused by the increase in the distance from the heel to the phalanx. Male mammary gland development, pubic hair is female-type distribution, penis and testicles are small. Severe cases are accompanied by mental retardation, cryptorchidism and hypospadias.

Cause

The causes of a beardless have the following:

1. The development of men's secondary sexual characteristics is not obvious, and the gonadotropin secreted by sex hormones in the body is impaired.

2. The formation of congenital testicular hypoplasia may be due to the egg cell in the process of maturation and division, the sex chromosome does not separate, forming an egg containing two X, if this egg combines with Y sperm to form 47,XXY fertilized eggs. If the spermatogenic cells do not separate during the first maturation and division of XY, the XY sperm is formed, and this sperm can form 47,XXY fertilized eggs in combination with X eggs. It is generally believed that most of the 47,XXY formation eggs are caused by the absence of sex chromosome segregation during mature division.

an examination

Related inspection

Trace element detection in human body

Whether a man has a beard is not morbid, it is necessary to judge the development of the whole body. If a man has no beard, but the genital organs and the secondary sexual characteristics mentioned above are all normal, it is not morbid. The starting age of the boy's growing beard is not exactly the same. Some years ago, some years later, are normal, and don't worry.

If you have entered puberty, you don't have a beard, the second sexuality is not obvious, and even beyond the puberty, there is still no development. This should be regarded as abnormal. It may be a gonadotropin that specifically regulates the secretion of sex hormones. The problem needs to go to the hospital for examination and treatment.

Differential diagnosis

The disease often needs to be differentiated from hypogonadotropic hypogonadism (HH). The latter testicles are small and soft, the external genitalia and second sexually developed diseases are poorly developed, male breast development is less common, the body is also taller, the upper and lower limbs are too long, the plasma gonadotropin reduces serum T significantly, and the seminiferous tubules Both Leydig cells have obvious abnormalities, and the karyotype is normal according to these different characteristics.

It is generally difficult to make a diagnosis before the developmental period. Infertility or sexual dysfunction is the main reason for the patient's visit. The two sides of the testicle are small, and the breast hypertrophy on both sides is a typical condition. X small body positive, karyotype is 47, XXY can definitely diagnose.

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