No armpit hair

Introduction The mane is located under the armpit and is the result of the adrenal gland beginning to secrete androgen. Once the armpits grow out of the armpits, they are often sweaty in the armpits. Mane is one of the first signs of your puberty. Everyone has a long hair, it helps to absorb sweat to prevent sweat from flowing down. No whisker hair and pubic hair were found in Klinefelter syndrome. Also known as congenital testicular hypoplasia or Klinefelter syndrome. The typical karyotype is 47,XXY, and the phenotype is characterized by testicular hypoplasia. Severe cases are accompanied by mental retardation, cryptorchidism and hypospadias.

Cause

The growth of the mane grows under the stimulation of the male hormone testosterone. The reasons for no mane are:

1. For some reason, the level of androgen produced by the adrenal cortex is low. At this time, there may be sparse bristles, which will not affect the ovary and ovulation and menstrual cycle, and will not affect sexual life and future fertility.

2. The armpit is not sensitive to or sensitive to androgen. At this time, even if the level of androgen in the body is normal, it will not grow mane, but this does not affect the development of the breast, nor does it affect the ovulation and menstrual cycle of the ovary. Will affect the sexual life and reproductive function after marriage.

3. There is also a non-long hair condition that is ovarian dysplasia or congenital absence of ovary in adolescent women. These people often affect the development of the breast, the menstrual cycle is also affected, and the body is short and the appearance is naive.

4. The formation of congenital testicular hypoplasia may be due to the egg cell in the process of maturation and division, the sex chromosome does not separate, forming an egg containing two X, if this egg combines with Y sperm to form 47,XXY fertilized eggs. If the spermatogenic cells do not separate during the first maturation and division of XY, the XY sperm is formed, and this sperm can form 47,XXY fertilized eggs in combination with X eggs. It is generally believed that most of the 47,XXY formation eggs are caused by the absence of sex chromosome segregation during mature division.

an examination

Related inspection

Estrogen endocrine function test

an examination:

It can be diagnosed according to the clinical symptoms of no hair. The specific symptoms of the hairless hair can also be judged by examining the content of the androgen testosterone in the body. It is generally difficult to make a diagnosis before the developmental period. Infertility or sexual dysfunction is the main reason for the patient's visit. The body type is higher, the bilateral testicles are smaller, and the breast hypertrophy on both sides is a typical condition. The slender figure is caused by the increase in the distance from the heel to the phalanx. Male mammary gland development, pubic hair is female-type distribution, penis and testicles are small. Severe cases are accompanied by mental retardation, cryptorchidism and hypospadias.

Differential diagnosis

Identification:

The disease often needs to be differentiated from hypogonadotropic hypogonadism (HH). The latter testicles are small and soft, the external genitalia and second sexually developed diseases are poorly developed, male breast development is less common, the body is also taller, the upper and lower limbs are too long, the plasma gonadotropin reduces serum T significantly, and the seminiferous tubules Both Leydig cells have obvious abnormalities, and the karyotype is normal according to these different characteristics.

diagnosis:

It is generally difficult to make a diagnosis before the developmental period. Infertility or sexual dysfunction is the main reason for the patient's visit. The two sides of the testicle are small, and the breast hypertrophy on both sides is a typical condition. X small body positive, karyotype is 47, XXY can definitely diagnose.

It can be diagnosed according to the clinical symptoms of no hair. The specific symptoms of the hairless hair can also be judged by examining the content of the androgen testosterone in the body.

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