Pathological hair loss

Introduction Normal people have about 40-100 hair loss per day on average, which is normal metabolism. The amount of hair that falls off every day is about the same as that of newborn hair, so it will not become thin. If the number of hair loss exceeds this number, and the hair is significantly thinner than before, it is pathological alopecia. If you don't have a lot of hair loss, but your hair grows very slowly and your hair is getting thinner, it is also a pathological hair loss. Eliminate mental depression. Unstable mental state, daily anxiety will lead to hair loss, the deeper the degree of depression, the faster the rate of hair loss. Therefore, frequent deep breathing, walking, and relaxing gymnastics can eliminate mental fatigue on the day. It is also essential to ensure adequate sleep and other details.

Cause

There are many factors leading to pathological alopecia, both congenital or hereditary factors, as well as acquired factors; both physiological and pathological causes. However, acquired factors, that is, some pathological factors caused by hair loss are most common, such as some mental stress, acute and chronic infectious diseases, various skin diseases, endocrine disorders, physical and chemical factors, neurological factors, nutritional factors, etc., can lead to hair loss.

an examination

Related inspection

Endocrine function test positron emission tomography (PET)

1, hair pull inspection

A positive hair pull test means that 2-8 hairs can be easily removed from any part of the scalp without pain. In the resting period of hair loss, hair loss loosening syndrome, alopecia areata and other hair onset, this experiment was positive.

2, endocrine examination

The examination of sex hormone levels has certain clinical significance for postpartum hair loss, menopause hair loss and hair loss caused by oral contraceptives; serum TSH examination is most valuable for the diagnosis of hypothyroidism.

3, nutritional metabolism check

Nutritional metabolic diseases such as iron deficiency, early laboratory tests confirmed that serum ferritin is less than 12ug / L for iron storage deficiency, while transferrin saturation is less than 0.15, whole blood FEP is greater than 1.78umol / L (100ug / dL Or two of FEP/Hb greater than 4.5 ug/gHb can be diagnosed as iron-deficient erythropoiesis alopecia. In the early stage of malignant malnutrition, due to insufficient long-term intake of protein, the formation of negative nitrogen balance in the body, blood and urine urea nitrogen decreased first, creatinine, creatinine decreased is also a sensitive indicator, low plasma total protein is the diagnosis of malnutrition alopecia condition.

4, other inspections

Systemic lupus erythematosus mainly checks for LE cells, anti-dsDNA or anti-sm antibodies, ANA immunofluorescence, etc., syphilitic alopecia must be tested for syphilis serology. It is suspected that the detection of HIV antibodies is most commonly caused by AIDS-induced hair and scalp diseases. The method is to use a peripheral blood lymphocyte for virus culture, the positive rate is more than 95%, and AIDS patients with hair scalp lesions, more than 70% of T helper factors (TH) fall below 0.15*109/L, while normal human blood TH The value is greater than 1.5*109/L.

Differential diagnosis

1, seborrheic alopecia: often appear in young and middle-aged people, the performance of the scalp has a thick oily secretion, the head is bright, sparse and thin, or dry hair, dandruff, dull, sparse and slender.

2, pathological hair loss: mainly due to virus, bacteria, high fever on the hair cells, inhibiting the normal division of hair cells, so that hair follicles in a state of shock leading to hair loss, such as acute infectious diseases, long-term use of certain drugs.

3, chemical hair loss: harmful chemical substances on the scalp tissue, hair follicle cells damage caused by hair loss

4, physical hair loss: air pollutants block hair follicles, harmful radiation and other causes of hair loss.

5, nutritional hair loss: digestive dysfunction caused by malnutrition leading to hair loss

6, obesity hair loss: a large number of saturated fatty acids in the body after the metabolism of waste, clogging hair follicles leading to hair loss

7, hereditary hair loss: hair loss is also hereditary, generally male dominant sexual inheritance, female recessive inheritance.

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