Cardiac dystrophy

Introduction Cardiac muscle A muscle tissue composed of cardiomyocytes. The generalized cardiomyocytes include specially differentiated cardiomyocytes that make up the sinus node, the intraventricular bundle, the atrioventricular junction, the atrioventricular bundle (ie Heath bundle), and Purkinje fibers, as well as the general atrial and ventricular muscles. Working cells. The first five species constitute the cardiac pacing conduction system, which contain little or no myofibrils, so they have no contractile function; however, they are self-disciplined and conductive, and are the functional basis of cardiac self-discipline activities; Two types of contraction are the functional basis of cardio-systolic activity. Cardiac tissue dystrophies are more common in cardiomyopathy.

Cause

Cardiomyopathy is a myocardial disease of unknown cause and is generally thought to be associated with viral infection, autoimmune response, genetics, drug poisoning, and metabolic abnormalities. It does not include specific cardiomyopathy with a clear cause or secondary to systemic disease.

an examination

Related inspection

Dynamic electrocardiogram (Holter monitoring) ECG

Due to coronary artery multi-vessel disease, even diffuse lesions caused by extensive myocardial ischemia, degeneration, necrosis and fibrosis, myocardial blood supply for a long time is insufficient, myocardial tissue dystrophies, atrophy, necrosis, resulting in fibrous tissue hyperplasia, which leads to Ischemic cardiomyopathy.

Differential diagnosis

Dilated cardiomyopathy: Dilated cardiomyopathy may be associated with certain factors. Myocardial damage caused by abnormal metabolism of bacterial drug poisoning is related, and viral myocarditis is considered to be the main cause. Sustained viral infection can cause or induce dilated cardiomyopathy by damage to myocardial tissue, autoimmune cells, autoantibodies, or cytokine-mediated myocardial damage. In addition, perinatal, alcoholism, anticancer drugs, myocardial energy metabolism disorders and neurohormone receptor abnormalities can also cause this disease.

Hypertrophic cardiomyopathy: may be related to autosomal dominant inheritance, about 1/3 of the family history, cardiac myosin heavy chain and cardiac troponin T gene mutation are the main pathogenic factors. In addition, abnormal metabolism of catecholamines, abnormal regulation of intracellular calcium, high blood pressure, high-intensity exercise, etc. can be used as a promoting factor for the onset of this disease.

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