Liver disease face

Introduction Hepatic disease is more common in patients with chronic hepatitis and cirrhosis, and is one of the common clinical manifestations of patients with liver disease. The face of liver disease is characterized by dry skin, dark complexion and darkness. The pigmentation of the skin on some patients' faces and other exposed parts may be more obvious, especially the pigmentation around the eyelids. The facial features of the liver disease are that the color of the facial skin is gradually darkened, the face is black and the gloss is not elastic, the skin is dry and rough, and even the "bronze" face appears; some patients are especially dark around the eye circle, a bit like "panda eyes"; some patients Small telangiectasia appears on the face or tip of the nose, like a delicate network. Medically, these characteristic changes in the face of patients with liver disease are called "hepatic disease face", which is caused by an increase in melanin production due to liver dysfunction.

Cause

The mechanism of the appearance of liver disease is not fully understood. Some scholars believe that the increase of estrogen in patients with chronic liver disease weakens the inhibitory effect of thiol groups on tyrosinase in the skin. As a result, tyrosinase increases the amount of tyrosine into melanin. To blacken the skin. Some scholars believe that the adrenal function of patients with cirrhosis is reduced, the function of adrenal medulla complex adrenaline is reduced, affecting pigment metabolism, pigment entering the skin, making the skin black. In addition, the sympathetic inhibition of melanogenesis in patients with cirrhosis is weakened, which promotes the production of melanin and enters the skin, resulting in a liver disease.

an examination

Related inspection

MRI examination of liver, gallbladder, pancreas and spleen by liver, gallbladder and spleen

Clinically, patients with liver disease face should be examined:

First, physical examination

Taking a medical history gives us a first impression and revelation, and also guides us to a concept of the nature of the disease.

Second, laboratory inspection

Laboratory examinations must be summarized and analyzed based on objective materials and medical examinations, and several possible diagnostics are proposed, and then further examinations are performed to confirm the diagnosis. Such as liver function, liver ultrasound and other tests.

Differential diagnosis

Identification:

Other factors of life can also lead to darkening of the face, such as lack of sleep, malnutrition and so on. There are also other diseases caused by reduced blood oxygen levels, such as pneumonia, high altitude, heart failure, asthma, pulmonary heart disease, constipation, abdominal pain, diarrhea can also cause, and kidney disease often causes dark complexion, and excessive fatigue It will also be caused. Some people are born with black skin. They must not point to the black people saying that they are liver disease faces and make jokes.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.