Vulvar hemangiopericytoma

Introduction to vulvar angioblastoma Vulvar vascular epithelial cell tumors are characterized by the proliferation of tumor cells outside the basement membrane, which may be benign or malignant. Malignant people can be called extravascular sarcoma, and can also be collectively referred to as angioendothelioma. basic knowledge The proportion of illness: 0.0003%--0.0007% Susceptible people: no special people Mode of infection: non-infectious Complications: hemangioma

Causes of vulvar vascular epithelioma

(1) Causes of the disease

Vulvar angioblastoma originates from the outer membrane cells of Zimmermann.

(two) pathogenesis

The tumor has a localized nodular shape with a clear margin and a thin layer of capsule. The average diameter is 4-8 cm. The cut surface is grayish to reddish brown, often accompanied by hemorrhage and cystic changes. Malignant necrosis can be seen.

Microscopic examination showed abundant blood vessels, the inner wall was lined with normal endothelial cells, the tumor cells were completely located outside the capillaries, and there was often a collagen fiber band between the blood vessels and the tumor cells. The tumor cells were arranged in a spiral or radial arrangement around the blood vessels and collagen fibers, with PAS. Or reticular fiber staining can clearly evoke blood vessel images. The histological identification of benign and malignant hemangiopericytoma is difficult. The malignancy usually manifests as a tumor with a diameter of more than 5 cm, cell pleomorphism, increased mitosis or regional necrosis. Not having the above performance can also be considered potentially malignant because about 20% of them may have local infiltration or hematogenous metastasis.

Immunohistochemistry showed vimentin strong positive, FXIIIa and HLA-DR were positive, but most of them only 5% to 20% of tumor cells stained.

Vulvar vascular epithelioma prevention

Regular physical examination, early prevention can improve survival rate, pay attention to follow-up.

Vulvar vascular epithelioma complications Complications

Transfer along blood vessels or lymph nodes.

Vulvar vascular epithelioma symptoms Common symptoms Shame lumps

It is often characterized by irregular swelling of the vulva slowly growing, painless, and the position of the mass is shallow and soft.

Examination of vulvar vascular epithelioma

Tumor marker examination, cytogenetic examination.

Histopathological examination, immunohistochemistry.

Diagnosis and diagnosis of vulvar vascular epithelioma

According to clinical manifestations and laboratory immunological examination, histopathological auxiliary examination can be diagnosed.

Good, histological differentiation of malignant hemangiopericytoma is difficult. It can be differentiated from other sarcoma of the vulva by histopathology, electron microscopy and immunohistochemistry.

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