Spindle cell lipoma
Introduction
Introduction to spindle cell lipoma Spindle celllipoma is a special type of lipoma, mainly found in male elderly (40 to 70 years old). It accounts for 1.5% of the occurrence of lipoma. basic knowledge The proportion of illness: 0.003%-0.009% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
The cause of spindle cell lipoma
(1) Causes of the disease
The cause is still unknown.
(two) pathogenesis
The pathogenesis is still unclear.
Prevention
Spindle cell lipoma prevention
There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.
Complication
Spindle cell lipoma complications Complication
There are generally no other complications.
Symptom
Spindle cell lipoma symptoms Common symptoms Slow growth
Clinically, it is often characterized by a slow-growing, painless mass. In general, the tumors are mostly single nodules with clear boundaries or envelopes. The diameter is 1 to 13 cm, usually less than 5 cm. The cut surface is yellow or grayish yellow, with grayish-white rubber-like areas, which occur in the back, the part, and the pole. Individuals can occur on the face, in the skin or under the skin, and grow slowly.
Examine
Examination of spindle cell lipoma
Histopathology: The tumor is encapsulated by a capsule, with or without a capsule, and invades the surrounding muscle. The tumor consists of mature adipocytes and uniform spindle cells, which are present in the mucinous matrix and the thick collagen fiber bundle, and the spindle cells are small. , with a single nucleus, nuclear prolongation to bipolar, CD34 staining positive, often along the collagen bundle, or in the form of an umbrella distributed between the fat cells, usually, the two cells are roughly the same number, mixed together or one each At the site, the whole tumor tissue contains many mast cells, which is a unique point of this tumor. There are not many tumor vessels in the tumor. Both spindle cell lipoma and pleomorphic lipoma show the aberration of nuclear chromosome 16q.
Diagnosis
Diagnosis and diagnosis of spindle cell lipoma
diagnosis
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Differential diagnosis
Fibrolipoma
Only fibrous tissue hyperplasia, no bundled spindle cells, no obvious mucinous interstitial increase.
2. Fibrosarcoma
No fat cells.
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