Pustular erosive dermatosis of the scalp

Introduction to scalp pustular erosive skin disease Erosivepustulardermatosis of thescalp is a rare non-infectious pustular dermatosis that was first reported and named by Pye in 1979. They reported 6 cases, characterized by: 1 in older women; 2 scalp pustules, erosion, scarring chronic lesions, often with scarring alopecia; 3 laboratory tests without special abnormalities, histopathology is non-special Heterotopic skin atrophy and chronic inflammatory changes; 4 antibiotic treatment is ineffective, and corticosteroids are effective for topical application. basic knowledge The proportion of illness: the incidence rate is about 0.005%-0.01% Susceptible people: no specific population Mode of infection: non-infectious complication:

Causes of scalp pustular erosive skin disease

(1) Causes of the disease

The etiology of this disease is unknown, no pathogenic bacteria were found in pus culture, and antibiotic treatment was ineffective. Therefore, it was caused by non-infection. Watanabe reported cases of Hashimoto's thyroiditis and autoimmune hepatitis, and immunoglobulin increased. The gamma globulin is increased, and abnormalities such as various autoantibodies are detected, suggesting that the disease may have a common pathogenic factor with autoimmune diseases.

(two) pathogenesis

Currently there are no related content description.

Prevention of scalp pustular erosive skin disease

There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Complications of scalp pustular erosive skin disease Complication

Symptoms of scalp pustular erosive skin disease Common symptoms Severe scalp and bloody scalp Irregular rupture pustular scarring

The cases reported so far are all female. The 6 cases originally reported by Pye et al. are 78-90 years old, all of whom are older. Although they are reported to be 92 years old and 91 years old, the age reported in Japan is small. For the 30s to 40s, the youngest is only 15 years old.

Skin lesions are pustules, erosions, scars and scarred alopecia patches that are confined to the scalp, mostly 1 or 2, diameters up to several centimeters to ten centimeters, round or irregular, clear boundaries The top of the head is the most common, followed by the lateral head or anterior head. The pustules are superficial, multiple, and the blister wall is loose. About half a grain of rice is large, can be scattered, can also be fused, recurring, erosion surface The upper cover has a yellow-brown to dark brown enamel, the hair at the lesion is detached, the lesion progresses slowly, the period of short illness is several months, and the length is up to 5 years or longer.

Examination of scalp pustular erosive skin disease

There are no special abnormalities in the laboratory tests.

Histopathology: skin atrophy and non-specific chronic inflammation of the dermis, skin atrophy, atrophy of the epidermis, dermis and hair follicles, inflammation mainly in the superficial dermis, infiltration of lymphocytes and plasma cells.

Diagnosis and differentiation of scalp pustular erosive skin disease

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

According to non-specific histopathological images, it is easy to distinguish from psoriasis, lichen planus, lupus erythematosus and the like.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.