Post-inflammatory release of elastic fibers with skin laxity

Introduction of elastic fiber release and skin relaxation after inflammation Post-inflammation of the elastic fiber with skin relaxation (postinflammatoryelastolysisandcutislaxa) is a rare chronic skin disease. basic knowledge The proportion of illness: 0.005% Susceptible people: more common in the past 1.5 to 4 years old children, mostly girls Mode of infection: non-infectious Complications: urticaria

Elastic fiber release after inflammation and the cause of skin relaxation

(1) Causes of the disease

The cause is unknown, may be due to allergic reactions to arthropod bites or solar radiation, may also be due to copper metabolism disorders, lack of elastic hard protease inhibitors, elastic tissue is easily caused by the dissolution of elastase.

(two) pathogenesis

The pathogenesis is still not clear, the allergic reaction of inflammatory arthropod bites or solar radiation, etc., causing the elastic tissue to be easily broken by the elastase.

Post-inflammation elastic fiber release with skin relaxation prevention

Try to avoid mosquito bites and direct sunlight. Try not to smoke, drink alcohol, or drink less tea.

Post-inflammation elastic fiber release with skin relaxation complications Complications urticaria

Benign reactivity changes, neck wrinkles, rash, loss of skin fullness, expansive shrinkage.

Post-inflammation elastic fiber loosening with skin relaxation symptoms Common symptoms Skin fullness loss Skin wrinkles Eosinophilia Itching papules Pain ESR increased scaly

The disease is most common in children with normal health of 1.5 to 4 years old, mostly girls. In the acute phase, there are rice granules and soybean-sized papules, which gradually develop into inflammatory plaques of broad bean size, urticaria or scaly plaques, consciously itching. It has a slight painful feeling. After a few days to several weeks, the skin becomes soft, thin, inelastic and atrophy, like wrinkled paper-like skin (degrees vary), can occur anywhere in the body, but it is more common in facial involvement. The child is old-aged, the scalp and palmar are often not tired. In some cases, erythema and plaque appear on the skin during sun exposure, and the itching is aggravated. New pimples and plaques may last for months or years, occasionally affecting In most parts, some patients had only mild systemic symptoms, increased erythrocyte sedimentation rate and increased granulocyte count, and one case reported aortic inflammation.

Examination of elastic fiber release and skin relaxation after inflammation

ESR increases and acidic granulocytes increase.

Histopathology: There are a large number of neutrophils and a small amount of eosinophils in the epidermis of the acute phase. The infiltration of lymphocytes and perivascular inflammatory cells is more obvious. Elastomeric fiber staining shows elastic fiber rupture or particle degeneration. In the chronic phase, dermal atrophy The upper part of the dermis is lack of elastic fiber, the lower part is degenerated, accompanied by a small amount of mononuclear cell infiltration, and collagen fiber degeneration can also occur, especially in the chronic phase.

Diagnosis and identification of elastic fiber release and skin relaxation after inflammation

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

The erythematous (Jadassohn-Pellrzzari type) cutaneous laxity has a soft and relaxed soft-like flattened bulge, and the disease manifests as atrophy.

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