Idiopathic skin calcification

Introduction to idiopathic skin calcification Calcinosiscutis is a disease caused by the deposition of insoluble calcium salts (mainly undetermined calcium phosphate or small amounts of calcium carbonate) in the skin or subcutaneous tissue. It can be divided into metastatic skin calcification, malnutrition calcification and special hair. Type 3 such as sexual calcification. basic knowledge The proportion of illness: 0.0021% Susceptible people: no specific population Mode of infection: non-infectious complication:

Idiopathic skin calcification etiology

(1) Causes of the disease

It is a disease caused by deposition of insoluble calcium salts (mainly undetermined calcium phosphate or a small amount of calcium carbonate) in the skin or under the skin.

(two) pathogenesis

Calcium deposits in previously damaged tissues, serum calcium and phosphorus levels are normal, internal organs are not invaded, and the pathogenesis is still unclear.

Idiopathic skin calcification prevention

Treat the underlying disease as much as possible and not abuse the vitamin D preparation.

Idiopathic skin calcification complications Complication

Symptoms of idiopathic skin calcification common symptoms skin calcium calcification abdominal wall extensive calcium deposition subcutaneous nodules papules

Can be divided into mass calcification and subepidermal calcification nodules.

Massive calcification

It has many large subcutaneous calcified masses, which can be associated with papular and nodular calcified skin lesions. This disease often has a family history and complicated hyperphosphatemia.

2. Subepidermal calcified nodule

Also known as skin stones, usually a single small bulging hard nodules, sometimes 2 to 3 nodules, the surface of the nodules are mostly scorpion-like, but the surface can also be smooth, common parts are facial, some cases have many Or even countless nodules, most of the patients are children, some cases have individual nodules at birth or no nodules before adulthood.

Examination of idiopathic skin calcification

Histopathology:

Massive calcification

There is a large amount of calcium in the subcutaneous tissue, and there is a foreign body reaction around it. In some cases, there is calcium deposition in the epidermis, and calcium can be discharged from the ulcer or through the epidermis.

2. Subcutaneous calcified nodules

Calcified substances are mainly located in the uppermost layer of the dermis, mainly dense calcified spheres, and some are one or several large homogenized calcified masses. The calcified spheres and clumps are coupled with intact nuclei, large Macrophages and foreign body giant cells can be seen around the mass, and the epidermis is thickened, and calcium particles are visible in the epidermis, suggesting that the epidermis is excreted.

Diagnosis and diagnosis of idiopathic skin calcification

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

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