Confluent reticulated papillomatosis

Introduction

Introduction to fusion reticular papillomatosis Confluent and reticulate papillomatosis (also known as cutaneous papillomatosis), Gougerot-Carteaud syndrome, first described by Gougerot and Carteaud in 1932, they divided the disease into three types: spotted papilloma , fusion reticular papillomatosis and coin-shaped fusion reticular papillomatosis. Occasionally in the double breast room, the skin lesions are flat, pigmented keratinized papules, partially fused into a network. basic knowledge The proportion of illness: 0.005% Susceptible people: no specific population Mode of infection: non-infectious Complications: pruritus

Cause

Causes of fusion reticular papillomatosis

(1) Causes of the disease

The cause is still unclear. It is thought to be related to Malassezia infection, but the antifungal treatment is not effective, or it is considered to be related to endocrine function changes, such as pregnancy, thyroid dysfunction, Cushing syndrome, etc., but most cases have no endocrine. The change is also considered to be a variant of acanthosis nigricans.

(two) pathogenesis

The pathogenesis is still unclear, and it is thought to be related to Malassezia infection, endocrine function changes, and also a variant of acanthosis nigricans.

Prevention

Invasive reticular papillomatosis prevention

The disease is a viral infectious disease, and its preventive measures are mainly for the cause, improve the physical condition of the body, and intake of foods with high vitamin C content, which can reduce the risk of infection. For patients exposed to this disease, care should be taken to clean the skin after contact and reduce the risk of viral infection. Patients with existing infections should be actively antiviral therapy to reduce the incidence of complications.

Complication

Concomitant reticular papilloma complications Complications pruritus

The disease occurs in the double-breasted room, and the lesion is a flat, pigmented keratinized papule, partially fused into a network. Mainly caused by skin damage, patients can be scratched by skin itching, some patients feel aversion to repeated skin damage caused by papilloma infection, often cut with a nail clipper, if the disinfection is not strict, can cause tetanus infection of skin mucosa, Should be brought to the attention of clinicians.

Symptom

Symptoms of fusion reticular papillomatosis Common symptoms Pimple round or oval dome... Itching

Occurs in adolescents, women are more common, skin lesions start from a reddish papule, diameter 1 ~ 2mm, hemispherical or flat, gradually increased, up to 0.5cm, grayish brown, slightly keratinized surface Similar to flat warts, the papules are constantly increasing, and they are fused into a sheet or a mesh. They are clinically easy to be diagnosed as tinea versicolor, which is fused into a round or oval shape, called a coin-like fusion reticular papillomatosis. The damage usually occurs in the breast room and the middle of the back. Later, it gradually spreads to the breast, upper abdomen, pubic bone, upper back and ankle. Sometimes it can affect the shoulder, neck, armpit and armpit. When the armpit is involved, the skin is gray. Brown, papules are not obvious, wrinkles deepen, keratinization is obvious, like acanthosis nigricans, mucous membranes are not involved, generally no symptoms, occasional itching, slow development of the disease, can tend to be stable.

Examine

Examination of fusion reticular papillomatosis

Histopathology: mild hyperkeratosis, papillary hyperplasia, widening of epidermal processes, atrophy between the two nipples, and increased pigmentation in the basal layer.

Diagnosis

Diagnosis and diagnosis of fusion reticular papillomatosis

diagnosis

According to the incidence of adolescents, pigmented keratotic papules are more common in the milk room, often merged into a network, which can be diagnosed.

Differential diagnosis

1. Facial plaque: The appearance of skin lesions is sometimes similar to this disease. The fungal microscopy is positive and antifungal treatment is effective.

2. Acanthosis nigra: It occurs in the wrinkles of the skin, the skin is thickened, the skin lines are deepened, and the pigmentation is obvious.

3. Symptoms of sacral epidermis: a single lesion is like a flat wart, and the lesions are widespread, more common in the back of the hands and feet and the trunk.

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