Connective tissue mole

Introduction to connective tissue Connective tissue (connectivetissusnevus) is rare, a hamartoma mainly composed of collagen fibers, which can exist alone or in combination with other diseases, and is acquired or congenital. Occurs in the trunk, most commonly seen in the lumbosacral region, skin lesions are single, but often multiple, the latter can be arranged in a strip. basic knowledge The proportion of sickness: 0.2% Susceptible people: no special people Mode of infection: non-infectious Complications: swelling

Connective tissue

(1) Causes of the disease

The cause is not very clear. It is generally considered to have a certain relationship with genetic, immune and viral infections. It is a multi-factorial disease. With the advancement of immunology, most connective tissue diseases are found to be associated with immunological abnormalities, such as inferior suppressor T cell function, humoral immune function, and some connective tissue diseases have autoantibodies, so this group of diseases is also included. An immune disease or an autoimmune disease. After the development of rheumatology, connective tissue disease was summarized in rheumatism. Although this group of diseases is not too common, the condition is often more serious, and some can affect life. Corticosteroids and immunosuppressive agents have a good effect and can alleviate the condition, but they cannot cure.

(two) pathogenesis

The pathogenesis is still unclear.

Connective tissue prevention

Prevention of this disease should be kept warm to prevent cold, it is also important not to overwork.

(1) Adhere to regular treatment and avoid and reduce the side effects of hormones, immunosuppressants, and non-steroidal drugs.

(2) Adhere to functional exercise and enhance autoimmune function.

(3) Life should be regular, moderate work and rest, and appropriate rest when symptoms are significant.

(4) Pay attention to the warmth of the extremities, avoid pregnancy, overwork and severe mental stimulation.

Connective tissue fistula Complications swelling

Most of the disease has grown slowly, or has remained unchanged for many years, but rarely spontaneously degenerates. Because the skin integrity is destroyed, it may cause skin bacterial infection or fungal infection due to scratching, usually secondary to low body constitution, or long-term use of immunosuppressive agents and fungal infections such as nail fungus, such as concurrent bacterial infection may have fever , skin swelling, ulceration and purulent secretion and other performance. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.

Connective tissue fistula symptoms common symptoms papular tuberous sclerosis osteosclerosis

The skin lesions can be lightly raised, plaques with a diameter of 1 to 15 cm. The color is yellowish to orange. The surface is similar to squid leather. It is found in the trunk. It is most common in the lumbosacral region, and the lesions are single, but often multiple. The latter can be arranged in a strip shape. In Proteus syndrome, the connective tissue sputum appears as a crotch, and the surface of the palm or palm is a brain-like mass.

1. Acquired connective tissue : According to the number of lesions and the main dermal fiber component, rash collagenoma, single collagenoma or single elastic tumor can be distributed clinically.

2. Hereditary connective tissue : including disseminated lenticular cutaneous fibrosis in Buschke-Ollendorff syndrome, familial cutaneous collagenoma and so-called squid skin spots found in tuberous sclerosis, Buschke-Ollendorff syndrome For autosomal dominant genetic diseases, extensive dermal papules and plaques can be seen. Asymmetry occurs in the trunk and limbs. The elastic fibers are thickened and the fiber diameters are significantly different. In some cases, the chain-chain desmosine is more than 3 to 7 times higher than normal. Accompanied by systemic fragility osteosclerosis, clinically asymptomatic, requiring X-ray diagnosis, showing increased focal sclerosing density, mainly found in long bones, pelvis and hands, patients with familial skin collagenoma, can appear on the back majority Symmetrical asymptomatic nodules, usually in adolescents, connective tissue spasm often associated with tuberous sclerosis, visible squid leather-like plaques, and typical skin lesions of sebaceous adenoma, periungual fibroma and grayish white Leafy spots are accompanied by.

Connection of connective tissue

1. Hereditary connective tissue X-ray diagnosis: visible focal sclerosis density increased, mainly found in long bones, pelvis and hands.

2. Histopathology: There were no significant differences between the many cases and normal findings in biopsy. In some cases, the number of collagen fibers or elastic fibers increased.

Connective tissue diagnosis and identification

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed. The hereditary connective tissue includes disseminated soy cutaneous fibrosis in Buschke-Ollendorff syndrome, which is clinically asymptomatic and requires X-ray diagnosis. It can be seen that the focal hardening density is increased, mainly in long bones, pelvis and hands.

This disease is generally not confused with other diseases.

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