Urinary alanine aminopeptidase

Urinary alanine aminopeptidase has a certain value in the diagnosis of kidney disease. When the kidney is damaged by pathological changes, the alanine aminopeptidase in the urine is significantly increased. Urinary alanine aminopeptidase can be used as a sensitive indicator for evaluating kidney damage. Normal values ​​of alanine aminopeptidase: male (12.6 ± 3.77) u / (g · cr); female (7.65 ± 2.46) u / (g · cr). Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: no information yet. Normal value: Urinary alanine aminopeptidase (male): 8.83-16.37u/(g·cr) Urinary alanine aminopeptidase (female): 5.19-10.11u/(g·cr) Above normal: Found in acute glomerulonephritis, acute pyelonephritis, acute renal failure and drugs (such as gentamicin, sulfonamides, etc.) caused by tubular damage. negative: Positive: Tips: Patients should wash the vulva before leaving the urine to avoid urine contamination of the vulva secretions. Women should prevent vaginal discharge from getting into the urine and be careful not to do this during the menstrual period. After discharging a part of the urine, take the middle part of the urine section. It should not exceed 2 hours after discharge until the test. Normal value Male (12.6 ± 3.77) u / (g · cr); Female (7.65 ± 2.46) u / (g · cr). Clinical significance Increase renal tubular damage caused by acute glomerulonephritis, acute pyelonephritis, acute renal failure, and drugs (such as gentamicin, sulfonamides, etc.). High results may be diseases: acute glomerulonephritis, acute pyelonephritis precautions 1, the patient washes the vulva before leaving the urine to avoid urine contamination of the vulva secretions. The container used should be clean and free from contamination. Do not mix chemicals such as detergents, disinfectants and preservatives to avoid affecting the inspection results. 2, women should prevent vaginal discharge into the urine, and pay attention to the inspection should not be done during the menstrual period. 3, take the middle section of urine: first discharge a part of the urine, take the middle part of the urine section. 4, should be sent immediately after the urine, urine specimens should be fresh, the maximum time after discharge to the test can not exceed 2 hours. 5. This enzyme assay requires simultaneous determination of urinary creatinine. 6, using mannitol, dextran, bile acid and other drugs, can increase the measured value. Inspection process Using urinary alanine p-nitroaniline (AlapNA) as a substrate, study the kinetic characteristics of AAP on this substrate, select the optimal reaction conditions, establish a serum AAP assay rate method and reference value, and observe the serum of patients with hepatobiliary disease. AAP acts on the kinetic characteristics of the substrate, selects the optimal reaction conditions, establishes the serum AAP assay rate method and reference value, and observes the serum AAP level of patients with hepatobiliary disease. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Nothing.

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