cerebrospinal fluid beta-endorphin

β-EP is a β-lipotypic C-terminal 31 peptide (ie, amino acids 61-91), and its analgesic effect is several times stronger than that of morphine. Mainly distributed in the hypothalamus and pituitary. Basic Information Specialist classification: examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Seen in Parkinson's disease. Normal value: β-EP: 44.78-47.6pg/ml Above normal: Acute central nervous system injury, cerebral embolism, ischemic stroke, unilateral middle cerebral artery occlusion cerebral embolism can be significantly increased for 40 hours, especially in patients with severe cerebral infarction, infarct size is significantly increased, including severe cerebral infarction The increase in β-EP content was more significant in patients with large infarct size and multiple infarcts. negative: Positive: Tips: The waist is taken from CSF1ml with aprotinin (7550KIU/ml) to inhibit peptide decomposition, centrifugation, and the supernatant is taken at -40 °C for use. Normal value 46.19 ± 1.41 pg / ml. Clinical significance Acute central nervous system injury, cerebral embolism, ischemic stroke, unilateral middle cerebral artery occlusion cerebral embolism can be significantly increased for 40 hours, especially in patients with severe cerebral infarction, infarct size is significantly increased, including severe cerebral infarction The increase in β-EP content was more significant in patients with large infarct size and multiple infarcts. Parkinson's disease has a reduced CSF content. Low results may be diseases: high results of Parkinson's disease may be diseases: cerebral embolism precautions The waist was taken from CSF1ml and aprotinin (7550KIU/ml) was used to inhibit peptide decomposition, and the precipitate was centrifuged. The supernatant was taken at -40 ° C for use. Inspection process Use radioimmunoassay. Not suitable for the crowd 1. If there is obvious papilledema or cerebral palsy, contraindications are contraindicated. 2. Patients who are in shock, exhaustion or endangered state and local skin inflammation, and lesions in the posterior cranial fossa are contraindicated. Adverse reactions and risks If the patient has symptoms such as breathing, pulse, or abnormal color during puncture, stop the operation immediately and deal with it accordingly.

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