Cerebrospinal fluid beta 2 microglobulin (beta 2-MG)

A method of examination of cerebrospinal fluid. Microglobulin is produced in lymphocytes. The cerebrospinal fluid specimens are sent for inspection immediately after collection. If they are placed for too long, the test results will be affected: if the cells are denatured and destroyed, the counting and classification will be inaccurate; some chemical substances such as glucose will reduce the decomposition content; the bacteria will cause autolysis to affect the detection rate of bacteria. . Basic Information Specialist classification: examination classification: cerebrospinal fluid examination Applicable gender: whether women are fasting: fasting Analysis results: Below normal: Found in acute or chronic glomerulonephritis, nephrotic syndrome and so on. Normal value: β2-MG: 1.16-1.38 mg/L Above normal: Found in proximal tubular damage, autoimmune diseases, malignant tumors, liver disease, rejection after organ transplantation, AIDS, etc. negative: Positive: Tips: Cerebrospinal fluid specimens are sent for inspection immediately after collection. If they are placed for too long, the test results will be affected. Normal value Cerebrospinal fluid 1.16 ~ 1.38mg / L. Clinical significance Increased in proximal tubular damage, autoimmune diseases, malignant tumors, liver disease, rejection after organ transplantation, AIDS and so on. Urine β2 microglobulin increased in acute or chronic glomerulonephritis, uremia, diabetic nephropathy, systemic lupus erythematosus involving renal disease, pyelonephritis, congenital Fanconi syndrome, Wilson disease, cadmium metal poisoning, and intake of Qingda Medicine, nifedipine (heart pain), tobramycin and other drugs. Reduced in acute or chronic glomerulonephritis, nephrotic syndrome and so on. Low results may be diseases: chronic glomerulonephritis, AIDS, nephrotic syndrome results may be high disease: acute glomerulonephritis considerations The cerebrospinal fluid specimens are sent for inspection immediately after collection. If they are placed for too long, the test results will be affected: if the cells are denatured and destroyed, the counting and classification will be inaccurate; some chemical substances such as glucose will reduce the decomposition content; the bacteria will cause autolysis to affect the detection rate of bacteria. . After the cerebrospinal fluid is extracted, three sterile tubes are generally divided. The first tube is used for bacterial culture, the second tube is used for chemical analysis and immunological examination, and the third tube is used for general traits and microscopic examination. The order of the three tubes should not be reversed. Due to the difficulty in collecting specimens, all inspection and testing procedures should be safe. Inspection process Radioimmunoassay. Not suitable for the crowd 1. If there is obvious papilledema or cerebral palsy, contraindications are contraindicated. 2. Patients who are in shock, exhaustion or endangered state and local skin inflammation, and lesions in the posterior cranial fossa are contraindicated. Adverse reactions and risks If the patient has symptoms such as breathing, pulse, or abnormal color during puncture, stop the operation immediately and deal with it accordingly.

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