Anti-thyroid peroxidase antibody

Thyroid peroxidase is the main antigenic component of thyroid microsomes, and its function is related to the synthesis of thyroxine. Anti-thyroid peroxidase antibodies or anti-thyroid microsomal antibodies may damage thyroid cells. The method for detecting anti-thyroid peroxidase antibodies is similar to anti-thyroglobulin antibodies. The clinical significance of anti-thyroid peroxidase antibody is similar to that of anti-thyroglobulin antibody, mainly for chronic lymphocytic thyroiditis, hyperthyroidism, primary hypothyroidism, and auxiliary diagnostic and therapeutic value. . Some patients are anti-thyroglobulin antibody negative, but anti-thyroid peroxidase antibody positive, so the simultaneous detection of both antibodies can increase the positive detection rate of anti-thyroid autoantibodies, and can be used as a clinical diagnosis and differential diagnosis of autoimmune thyroid An important basis for inflammation. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: fasting Tips: Try to eat less and eat as much as possible, and arrange your diet reasonably. Normal value The result of the test is ≤ 1:32 (indirect hemagglutination method). Clinical significance The detection rate of ATG in patients with Hashimoto thyroiditis can reach 90%-95%; the detection rate of hyperthyroidism patients varies from 40% to 90%. The high detection rate may be related to Hashimoto's hyperthyroidism in some cases. Related; the detection rate of patients with primary hypothyroidism is about 65%. The detection rates of subacute thyroiditis, thyroid cancer, and thyroid adenoma are very low. The detection rate of serum ATG in patients with connective tissue disease such as SLE is 20% to 30%. Patients with ATG-positive, especially high-level positive, should be cautious in their choice of treatment. A thyroid biopsy study of some patients with low ATG positives found that these patients had localized lymphocytic infiltration in the thyroid tissue. Precautions Each laboratory shall establish reference values ​​for the region based on its experimental conditions and methods. Inspection process The same indirect blood coagulation method. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.