Anti-skeletal muscle antibody

The anti-skeletal muscle antibody (antiskeletalmuscleantibody, anti-SMA) and antiacetyl-choline receptor (AchR) antibody target antigen are myosin and actin of skeletal muscle. Anti-skeletal muscle antibodies appear in myasthenia gravis, DM/PM, MCTD, and pernicious anemia. Normal person is negative. The anti-SMA positive rate of patients with simple myasthenia gravis is about 30%; almost all of them are positive with thymoma. There was no correlation between the anti-SMA and the clinical manifestations and test results of patients with myasthenia gravis. Some people had antibodies but no muscle weakness. Some people had myasthenia gravis but could not detect antibodies. The antibody titer did not change after removal of thymoma. Therefore, this antibody is considered to have no effect of blocking neuromuscular activity. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Positive myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus, pernicious anemia, Addison's disease (Addison's disease), thymoma, etc. Tips: After 8 pm on the day before the medical examination, you should start fasting for 12 hours, so as not to affect the test results. Normal value Indirect fluorescent immunoassay was negative. Clinical significance Positive myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus, pernicious anemia, Addison's disease (Addison's disease), thymoma, etc. Precautions First, the precautions before blood draw: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, after blood draw should pay attention to: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent medication and special physiological changes before the test. Inspection process Same as indirect fluorescent immunoassay. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.