HCO3-reabsorption test

The HCO3-reabsorption test is an ancillary test for checking the normalization of renal tubular acidification. Urine pH can be alkaline or acidic depending on the blood HCO3-level. 24h urine HCO4-only titratable acid normal, urinary calcium can be increased or normal (urine PCO2 can be injected into NaHC03 to alkalinize urine, when urine pH> blood pH, urine PCO2> blood PCO2, 2.66kPa or more Diagnostic significance, the doctor asks the patient to take the urine, the doctor takes the patient's fresh morning fresh urine 50 ml, and the obtained urine is sent to the laboratory for testing. After the result is obtained, the doctor informs the patient and judges the corresponding symptoms. To prescribe a prescription for treatment. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Tips: Keep regular routines and diet before checking to help the inspection go smoothly. Normal value The renal threshold of normal human bicarbonate is 25-26 mmol/L, and that of small infant is 22 mmol/L. There is often a limit to the reabsorption (active) of various substances in the renal tubules. Comparing the quality and quantity of primary and final urine, it can be found that the amount of raw urine produced by adults is about 180L per day, but the final urine volume is only 1.5L per day, indicating that the renal tubular reabsorption amount is 99%. Clinical significance Abnormal results: bicarbonate ion excretion fraction = urinary bicarbonate ion content x plasma creatinine content / plasma bicarbonate ion content x urine creatinine content. The renal threshold of bicarbonate in children is reduced to below 17-20 mmol/L. The people who need to be examined: suspected to be dysfunction of glomerular acidification. Precautions Taboo before the examination: Maintain regular routines and diet to help the inspection proceed smoothly. Requirements for inspection: 1. The specific methods of this test are slightly different from each scholar's report, but do not affect the test results. 2. Strict aseptic operation should be performed when indwelling the catheter. The doctor asked the patient to dispel their ideological concerns and cooperate with the trial. According to the doctor's instructions, the patient actively cooperated with the doctor for examination, and the doctor carefully examined and carefully observed the results. Inspection process The doctor took the patient's urine, and the doctor took 50 ml of fresh urine in the morning, and sent the obtained urine to the laboratory for testing. After the result was obtained, the doctor informed the patient and judged the corresponding symptoms. The abnormal result was prescribed. treatment. The renal threshold of bicarbonate in children decreased to 17-20 mmol/L or less (normally 25-26 mmol/L, 22 mmol/L in small infants), even if plasma HCO3-normal, due to decreased renal threshold, HCO3- in the filtrate A large amount is discharged from the urine, causing acidosis. Not suitable for the crowd Inappropriate people: Generally, there is no suitable for the crowd. Adverse reactions and risks No related complications or hazards.

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