Animal experiment

Animal experiments are scientific experiments in which animals are used in order to obtain new knowledge about biology, medicine, etc. or to solve specific problems. Animal experiments must be carried out by or under the direction of a trained person with a research degree or technical expertise. Laboratory animal science is formed alongside biomedical science through a lengthy animal experiment. However, the rapid development of experimental animal science has made the research value of experimental animals not only limited to biological sciences, but also closely linked with many fields of scientific experimental research, becoming an essential part of ensuring modern scientific experimental research. condition. In many fields of scientific research, experimental animals serve as a very important safety test, effect test, and standard test. Basic Information Specialist classification: check classification: Applicable gender: whether it is fasting: Tips: Pay attention to the quality of experimental animals. Normal value no. Clinical significance The ultimate goal of the development of experimental animal science is to use human life phenomena to promote human life, explore human life mysteries, control human diseases and aging, and prolong human life. With the rapid development of medical biological sciences, it is recognized that the public hazard problem has not only become a major social problem for food, population, and the elderly, but also involves the survival of animals living on the earth, such as industrial pollution, food pollution, and drug toxicity. Etc., all directly affect human health, and the study of these problems will ultimately be clarified through animal experiments (including the development of animal disease models, etc.). Therefore, the importance of experimental animal science, especially experimental animals, is increasingly recognized by people. It has been regarded as the pillar of human pursuit of a happy life, so experimental animal science is also called life science. To this end, advanced countries have given high priority to the development of experimental animal sciences, and the economic materials and technical forces they invest in can almost be compared with the development of atomic energy science, and its significance can be imagined. Precautions 1. The results of animal experiments cannot be completely used clinically without mechanical or unanalyzed; 2. Select animals that have commonality with human diseases for experimentation; 3. Pay attention to the quality of experimental animals. Inspection process For example, the virulence test of mice with freeze-dried live Japanese encephalitis vaccine: (1) Pathogenicity test in the brain The production of the poisonous batch was inoculated with 10 mice weighing 12 to 14 g, and each brain was injected with 0.03 ml. Those who died within 3 days after inoculation were not counted, and should be observed for 14 days. If there is a small white rat after 3 days, the pathogenicity should be determined by killing the brain. The virulence in the brain of the mouse should not exceed 3.0 LogLD50/0.03ml, and the mice are injected subcutaneously with 0.1ml10-1 diseased rat brain suspension. Subcutaneous pathogenicity test, observed for 14 days, should be healthy. (2) Subcutaneous infection in human brain test The production of the poisonous batch was inoculated into 10 mice of 10-12 g body weight, each subcutaneous injection of 0.1 ml, while the right side of the brain was empty, observed for 14 days, should be healthy. According to the results, the virulence of freeze-dried Japanese encephalitis live vaccine was evaluated. Adverse reactions and risks There are no related complications and hazards.

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