C-myc gene (C-myc)

The c-myc gene is not only a translocation gene, but also a regulatable gene regulated by various substances. It is also a gene that allows cells to proliferate indefinitely, obtain immortalization function, and promote cell division. Myc gene participates in cells. Withered, the c-myc gene is involved in the development of various tumors. The myc gene localizes to the chromosome 8q24, IgH, IgK, Igλ chain gene loci at 14q32, 2P13 and 22q11, respectively. In BL cells, there is often a translocation between the C-myc gene locus and the Ig gene locus, ie C -myc translocation to the highly active transcribed region of the Ig site, thereby forming a highly transgenic rearranged gene, triggering C-myc transcription, enhancing C-myc expression, promoting cell malignant transformation, and finally leading to tumorigenesis. Basic Information Specialist Category: Oncology Inspection Category: Genetic Testing (DNA) Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: No expression or low expression. Positive: Found in various tumors, such as lung cancer, stomach cancer, breast cancer, colon cancer, cervical cancer, certain neuroblastic diseases. Tips: The inspection process is strictly to avoid pollution. Normal value No expression or low expression. Clinical significance Over-expressed, found in various tumors such as lung cancer, stomach cancer, breast cancer, colon cancer, cervical cancer, certain neuroblastic diseases, granulocyte leukemia, retinoblastoma, osteosarcoma, chondrosarcoma, chordoma, fat Sarcomas, rhabdomyosarcoma, Hodgkin's disease, and head tumors all have amplification or overexpression of the myc gene. Positive results may be diseases: lung cancer, breast cancer, stomach cancer, cervical cancer, colon cancer considerations 1, no absolute or relative contraindications. 2. The inspection process is strictly avoided. Inspection process Take the correct check. Not suitable for the crowd Those who do not have an indication for examination should not be examined. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.

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