Down Syndrome Screening

Down's syndrome screening is to test the blood of pregnant women, to detect the concentration of alpha-fetoprotein, chorionic gonadotropin and free estriol in maternal serum, combined with the expected date of birth, weight, age and gestational age at the time of blood collection. A method for detecting the risk factor of a birth-born defect fetus is calculated. To determine the extent to which the fetus has a dangerous degree of Down's syndrome. Down's syndrome is a common chromosomal disease in humans. Because of the severe mental retardation of children with Down's syndrome, life can't take care of themselves. Almost all developed countries will perform Down's screening on pregnant women. Basic Information Specialist classification: eugenics and superiority examination classification: blood examination Applicable gender: whether women are fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Generally it is normal. Positive: Those at high risk should be further examined to rule out the possibility of congenital diseases. Tips: When you are doing a Down's screening, check the fasting water after 12pm the day before. Normal value The blood glucose level was <7.8 mmol, which was negative. Clinical significance High-risk pregnant women with certain birth defects are found in pregnant women through economical, simple and non-invasive methods to further confirm the diagnosis and minimize the birth rate of abnormal fetuses. The prenatal screening usually refers to the detection of a high-risk pregnant woman with a congenitally defective fetus through the detection of a maternal serum marker. Abnormal result The blood test screening value is greater than 1/270 (high-risk population), and it is recommended that the pregnant woman undergo further amniocentesis. Pregnant women in the population to be examined (within 16 to 18 weeks of gestation). Positive results may be diseases: considerations for children with Down syndrome In general, when doing Down's screening, check the fasting water after 12 o'clock the night before, and the next morning, go to the hospital for an empty stomach (fasting is not necessary). In addition, the examination is also related to the menstrual cycle, weight, height, accurate gestational age, and gestational age. It is best to consult the doctor for other preparations before the examination. Inspection process The best time to perform screening is the 9th to 14th week of pregnancy, which is called early pregnancy screening. If you miss this period, you need to enter the second trimester screening. Although the risk calculation can also be performed, if the final diagnosis is positive. Damage to the mother is large. Regardless of the early and mid-term, the pregnant woman can get the screening results within one week after the blood is drawn. If the result is high risk, there is no need to panic, because the diagnosis should be further confirmed by the villus biopsy (early), amniocentesis and fetal chromosome examination (interim). . Not suitable for the crowd 1. Pregnant women who have taken some medications may affect the results of the examination, so they should be avoided during the examination. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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