Basic fetal protein (BFP)

Fetal basic protein (BFP) was first discovered in fetal and intestinal tissues. BFP is present in a variety of cancerous tissues. Electrophoresis moves in the gamma-globulin region. BFP from normal serum is derived from liver and brain tissue. The increase in basic fetal protein is seen in: primary liver cancer, cholangiocarcinoma, gallbladder cancer, pancreatic cancer, and secondly, the judgment of clinical anticancer effect of gastric cancer and liver cancer and the monitoring of postoperative recurrence have certain significance. . Benign diseases also have a certain increase, and the positive results should be combined with clinical analysis. Basic Information Specialist classification: Oncology examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Generally it is normal. Positive: Found in liver cancer, pancreatic cancer, gallbladder and biliary cancer. Tips: Taboo excessive fasting, diet, drinking and smoking, so as not to affect certain test results. Normal value The serum level of normal people is very small, serum <80μg / L. 99% is below 100 ng/ml, with an average of 50 ng/ml, and >100 ng/ml is abnormal (Ishii Enzyme Linked Immunosorbent Assay). Normally negative. Clinical significance Abnormal result 48% of BFP in serum of patients with malignant tumors is above 100 ng/ml. The most positive rates were liver cancer, pancreatic cancer, gallbladder and biliary tract cancer, followed by breast cancer and leukemia, esophageal cancer and Hodgkin's disease. Gastric cancer and colon cancer increase with the progression of the disease. BFP can be reduced to a near normal high value when the treatment is effective, and can be increased when it is re-issued. If the BFP is more than 200ng/ml, and the liver cell damage can be ruled out, it is liver cancer. Among benign diseases, especially hepatitis, cirrhosis and aplastic anemia, about 50% of BFP may have abnormal values. Patients who need to be examined for liver cancer, pancreatic cancer, gallbladder, biliary tract cancer, breast cancer, leukemia, esophageal cancer, Hodgkin's disease, gastric cancer, colon cancer are best to do this test, so that the positive results should be combined with clinical analysis. . It is best for the elderly to do regular tests, and the average person should also check to prevent the disease. Positive results may be diseases: primary liver cancer, liver cancer, biliary tract cancer, gallbladder cancer, leukemia, Hodgkin's disease, breast cancer, hepatitis, gastric cancer precautions Taboo before the test: in a quiet state, living and eating in a daily state, taboo excessive fasting, diet, drinking and smoking, so as not to affect certain test results. Requirements for inspection: There is no special requirement for the specimen, and the fasting serum can be used. Follow the doctor's request. Inspection process As long as the serum is taken from the examiner, the doctor will use the main reagents and main instruments to separate and detect the serum, and determine the amount of fetal basic protein in the serum. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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