Dissolution time of euglobulin

The function of the fibrinolytic system in the human body plays a positive role in maintaining the normal flow of blood. If this function is excessive, it will cause the blood coagulation to decrease. The euglobulin lysis time is a preliminary screening test for detecting the function of the fibrinolytic system. It can roughly reflect the fibrinolytic activity, check for the presence or absence of latent fibrinolytic activity, or follow up as a thrombolytic therapy. The euglobulin contains components such as fibrinogen, plasminogen and plasminogen activator. Under normal circumstances, the euglobulin in the blood is stable. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Seen from various causes of fibrinolytic system hyperfunction, DIC. Normal value: Thrombin method: 100-150min Above normal: A slightly higher height is normal. negative: Positive: Reminder: Observe the end point without seeing the floc. Normal value The calcium addition method is greater than 120 min; the thrombin method is added for 100 to 150 minutes. Clinical significance Shortening of ELT (less than 70 min) indicates hyperfibrinoactivity, found in primary fibrinolysis and DIC. Low results may be diseases: diffuse intravascular coagulation, primary fibrinolysis 1. Steps 1 to 2 should be completed within 15 minutes. 2. The observation end point is based on no flocculation. 3. When plasminogen is almost depleted, this test may be a negative reaction. 4. Use borate buffer (pH 9.0) in the calcium addition method instead of barbiturate sodium acetate buffer (pH 7.4). Inspection process 1. Preparation of fibrin plate: 0.3 ml of thrombin and 30 ml of 1.5 g/L fibrinogen were quickly mixed in a glass dish, placed in a horizontal position, and allowed to solidify to form a 1 mm thick fibrin plate. 2. 0.03 ml of the test plasma which was anticoagulated with sodium citrate was dropped on a circle marked on the fibrin plate and placed at 37 ° C for 18 h. 3. Measure the area of ​​the fibrin plate that is dissolved. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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