serum cholesterol ester

Cholesterol is mainly formed in the liver, accounting for three-quarters of total cholesterol, and its changes are basically consistent with total cholesterol. Reduce acute hepatitis, severe cirrhosis, and hepatitis. Identification of intrahepatic and extrahepatic jaundice (increased total cholesterol in biliary obstruction, normal cholesterol ester/total cholesterol ratio; normal or decreased total cholesterol in liver jaundice, decreased cholesterol ester/total cholesterol ratio). Basic Information Specialist classification: Infectious disease examination and classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: When checking blood lipids, blood should be taken after 12 hours of fasting, no alcohol and high-fat diet within 24 hours, avoid taking related drugs, and do not exercise vigorously. Normal value The enzyme rate method (37 ° C) 2.34 ~ 3.38 mmol / L (90 ~ 130 mg / dl) accounted for 0.70 ~ 0.75 (70% ~ 75%) of total cholesterol (cholesterol ester = total cholesterol - free cholesterol). Clinical significance Reduce acute hepatitis, severe cirrhosis, and hepatitis. Identification of intrahepatic and extrahepatic jaundice (increased total cholesterol in biliary obstruction, normal cholesterol ester/total cholesterol ratio; normal or decreased total cholesterol in liver jaundice, decreased cholesterol ester/total cholesterol ratio). Low results may be diseases: hepatitis, cholestatic jaundice, fulminant hepatic failure (1) When checking blood lipids, blood should be taken after 12 hours of fasting, no alcohol and high-fat diet within 24 hours, avoid taking related drugs, and do not exercise vigorously. The position has an effect on the determination of blood lipids. Generally, the venous blood is taken in the sitting position, and the time for stopping the blood band should not exceed 1 min, so as not to increase the blood lipid. (2) Since the blood lipids vary greatly within the individual, it is best to measure the average two or three times (one time per week). (3) Many drugs that affect the determination of blood lipids, such as antiepileptic drugs, high dose cortisone, levodopa, adrenaline, stupid barbital, androgen, cinchon, chlorpromazine, cortex Steroids, vitamin C, etc.; can reduce cholesterol: tetracycline, erythromycin, isoniazid, metobutanol, phenformin, clofibrate, niacin, estrogen, paromomycin, adrenal gland Corticosteroids, levothyroxine, insulin, etc. (4) Total cholesterol has a tendency to increase with age. Mental workers are higher than manual workers. Because of mental stress, cholesterol can rise. Young women are younger than young men. Women surpass men of the same age after menopause. (5) Clinical total cholesterol measured value is greater than 8.6mmol / L, considered to have atherosclerotic cardiovascular disease; less than 2.5mmol / L, often accompanied by severe liver dysfunction, and suggest a very poor prognosis. Inspection process (1) Pipetting serum samples, standards, and water (blank) each at 20 μl. (2) Add 2 ml of enzyme reagent and mix for several seconds with a vortex mixer. (3) Insulation at 37 ° C for 10 to 15 minutes. (4) Colorimetric. Zero the reagent blank. The absorbance values ​​of the standard and serum samples were read separately. Not suitable for the crowd There are no special taboos. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.