Fibrinolysis time

The function of the fibrinolytic system in the human body plays a positive role in maintaining the normal flow of blood. If this function is excessive, it will cause the blood coagulation to decrease. The euglobulin lysis time is a preliminary screening test for detecting the function of the fibrinolytic system. It can roughly reflect the fibrinolytic activity, check for the presence or absence of latent fibrinolytic activity, or follow up as a thrombolytic therapy. The euglobulin contains components such as fibrinogen, plasminogen and plasminogen activator. Under normal circumstances, the euglobulin in the blood is stable. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Reminder: The plasma sample to be tested can not be frozen or thawed, otherwise its activity is significantly reduced. Normal value 10 to 40 mm2. Clinical significance When the primary or secondary fibrinolysis is hyperactive, the dissolution area of ​​the fibrin plate can be increased, and the significance is consistent with ELT. High results may be diseases: precautions for primary fibrinolysis (1) The plasma sample to be tested cannot be frozen or thawed, otherwise its activity is significantly reduced. (2) Urokinase can be used as a standard reagent, diluted to different levels, and urokinase is placed on the fibrin plate in the same manner for each test. (3) The test should be performed immediately after blood collection. Inspection process (1) Preparation of fibrin plate: 0.3 ml of thrombin and 30 ml of 1.5 g/L of fibrinogen were quickly mixed in a glass plate, placed in a horizontal position, and allowed to solidify to form a 1 mm thick fibrin plate. (2) 0.03 ml of the test plasma which was anticoagulated with sodium citrate was dropped on a circle marked on the fibrin plate and placed at 37 ° C for 18 h. (3) Measure the area of ​​the fibrin plate to be dissolved. Not suitable for the crowd Hemophilia and diffuse intravascular coagulation. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.

Was this article helpful? Thanks for the feedback. Thanks for the feedback.