reticulopoietic index
Reticulocyte count is based on its ratio to mature red blood cells. Anemia patients will inevitably lead to an increase in reticulocyte counts due to a decrease in the number of red blood cells. This error can be corrected by the ratio of red blood cells. However, in normal people, the reticular structure disappears in the blood circulation for about 1 day. In anemia patients, due to the increase of erythropoietin, the bone marrow often releases the reticulocytes into the blood in advance, causing the reticulocyte red blood cells to mature in the blood significantly, resulting in blood. In order to eliminate the increased number of false-positive reticulocytes, Finch proposed to use the reticulocyte production index (RPI) to correct it during anemia. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Keep a normal mindset. Normal value RPI = 1.0. Clinical significance (1) In hemolytic anemia, if the bone marrow function is normal, the RPI is increased by 3 to 7 times. (2) In hemolytic anemia, if the RPI of the bone marrow function is impaired and the degree of anemia is inconsistent, it is only increased by <2 times. (3) RPI is reduced, while the bone marrow contains many nucleated red blood cells with ineffective red blood cell production. Precautions (1) In recent years, ICSH and the National Committee for Clinical Laboratory Standards (NCCLS) define reticulocytes: reticulocytes do not contain nucleus, but with new methylene blue staining, it can still be found to contain ribonucleic acid. At least two or more red blood cells of the particles. (2) One method of counterstaining has a tendency to decrease, and the second method of counterstaining makes the particles difficult to distinguish, so the reticulocyte count is not counterstained. Inspection process (1) The hematocrit is measured while measuring the number of reticulocytes in the patient. (2) Determination of the ripening time of reticulocytes in the blood. (3) The reticulocyte production index was determined according to the following formula. Not suitable for the crowd Have a coagulopathy such as hemophilia. Adverse reactions and risks Risk of infection: If you use an unclean needle, you may be at risk of infection.
The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.