granulocyte colony stimulating factor

Colony-stimulating factor (CSF) includes granulocyte colony-stimulating factor (G=CSF) that enables granulocyte colony forming units (CFU-G) to form neutrophil colonies, enabling mononuclear-macrophage colony forming units (CFU). -GM) macrophage colony factor (M=CSF) that forms mononuclear-macrophage colonies, and granulocyte-macrophages that enable CFU-GM to form mononuclear-macrophage and neutrophil mixed colonies Colony stimulating factor. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: The significance of CSFs in the diagnosis of hematological diseases. Early detection of neutropenia and severe aplastic anemia after bone marrow transplantation, CSFs activity can be measured in the urine of patients within the first 5 days. Tips: Keep a normal mindset. Normal value Enzyme immunoassay (EIA) was negative. Clinical significance Abnormal results (1) The significance of CSFs determination in blood system diseases Early detection of neutropenia and severe aplastic anemia After bone marrow transplantation, CSFs activity can be measured in urine of patients within the first 5 days. At the same time, the production of such CSFs may be due to the activation of the body's immune system, especially to the activation of cells produced by CSFs. The detection of CSFs has certain significance for the pathogenesis, diagnosis and therapeutic observation of blood system diseases. Positive results may be diseases: myelodysplastic syndrome considerations Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Different laboratory items should be asked by the doctor and treated differently. Some companies offer ELISA kits. The first antibody has been coated, so the first step can be omitted. Refer to the instruction manual during operation. Inspection process There are also some differences in the reference values ​​provided by various methods, and it is necessary to expand the scope of detection and uniform standards. However, the detection of serum G-CSF, GM-CSF, EPO, IL-3 and other levels is of great significance in the pathogenesis, diagnosis and therapeutic observation of blood system diseases. In particular, the detection of G-CSF levels can be used as an early, rapid and sensitive indicator of bacterial infections. It has been shown that serum G-CSF assay is more sensitive than acute phase-reactive protein (CRP). Therefore, with the standardization and standardization of various CSFs detection methodologies, the determination of CSFs will have broader clinical application prospects. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally not.

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