acanthocytes

The acanthocyte red blood cells have pinpoint-like protrusions on the surface, and the spacing is irregular. The length and width of the protrusions vary. There are more blood smears in patients with beta lipoprotein deficiency. Also seen in splenectomy, alcoholic liver disease. Note the difference between shrinking red blood cells. The periphery of the wrinkled red blood cells is arranged in a zigzag shape, the size is equal, and the outer end is sharp. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: not fasting Tips: Before the examination, the diet is light and alcohol is prohibited. Normal value <0.3%. Clinical significance Abnormal results: Increased spiny polycythemia (hereditary β-lipoprotein deficiency), thalassemia, chronic liver disease, cirrhosis, acquired low β-lipoproteinemia, hemolytic anemia, pyruvate kinase deficiency, uremia, low After potassium and splenectomy. People who need to check: Anemia, liver abnormalities, uremia. Precautions Before the test: Do not drink alcohol, do not take medicine casually. Inspection process Dilute the blood with isotonic dilution, and then drop it into the blood cell counter. Then, under the microscope, count the number of red blood cells in a certain range. After conversion, the number of red blood cells per liter of backlog can be obtained. The traditional red blood cell dilution is Hayem liquid, which is prepared by dissolving sodium chloride, sodium crystallization sulfate and high mercury chloride in distilled water. The function of sodium chloride is to adjust the osmotic pressure, and sodium sulfate can increase the density and prevent cell adhesion and oxidation. High mercury is a preservative. The main disadvantage of this reagent is that in patients with hyperglobulinemia, red blood cells are easily coagulated due to globulin precipitation. Recently, methanol citrate dilutions have been widely used. The advantages of this solution are that they are simple to prepare, do not agglutinate red blood cells, and still have a normal disc shape after an hour of dilution. In normal cases, normal saline or 1% formaldehyde is added. The raw saline solution can be diluted with somatic red blood cells. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally no complications and harm.

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