Red blood cell distribution width (RDW)

The red blood cell distribution width (RDW) is a parameter reflecting the heterogeneity of red blood cell volume size, often the coefficient of variation of the measured red blood cell volume. This is a parameter measured by a blood analyzer that reflects the heterogeneity of peripheral red blood cell volume. In short, it is an objective indicator that reflects the size of red blood cells. Morphological classification of anemia is generally performed by two parameters, RDW and MCV. Combined with MCV, morphological classification of anemia can be performed, especially for the early diagnosis of iron deficiency anemia. Efficacy and prevention and the identification of iron deficiency anemia and globin-forming anemia are important. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: It is not advisable to transfuse blood before examination, and it is not appropriate to participate in strenuous exercise. Normal value The reference value is 10-16% for men, 10-16% for women, and 10-18% for newborns. Clinical significance Abnormal results: MCV is reduced and RDW is normal: Small cell homoemia. Common in light thalassemia, chronic diseases, children. MCV decreases and RDW rises: Small cell heterogeneity anemia. Common in iron deficiency anemia, beta-thalassemia, hemoglobin H disease, hemoglobin S disease. MCV is normal and RDW is normal: Normal cell homoemia. This is the case for normal people. Other abnormalities may include chronic diseases, chronic liver disease, acute bleeding, chronic lymphocyte leukocytes, chronic myeloid leukemia, and after chemotherapy. MCV is normal and RDW is raised: Normal cell heterogeneity anemia. Such as early or mixed nutritional deficiency, hemoglobin abnormal anemia, myelofibrosis, myelodysplasia, iron granulocyte anemia. MCV rises and RDW is normal: Large cell homoemia. Such as aplastic anemia, pre-leukemia, elevated condensation agglutinin. MCV rises and RDW rises: Large cell heterogeneity anemia. For example, megaloblastic anemia caused by folic acid or vitamin B12 deficiency, and some sickle cell anemia. Need to check patients with ischemic anemia and mild Mediterranean anemia in patients with iron deficiency anemia, etc. People who need to check: Anemia, globin production disorders, acute bleeding. High results may be diseases: iron deficiency anemia considerations (1) Various types of blood cell counters, especially imported instruments, most of which require heparin intravenous anticoagulation, but most hospitals use peripheral blood, so the normal blood in the area should be investigated before applying the counter. Reference. (2) When collecting blood, care should be taken to avoid mixing the cotton fibers into the suspension to prevent the counting of the holes from being inaccurate. (3) Pay attention to check the power supply, voltage, and inspection preparation before starting the machine. (4) The diluent should be kept between 18 and 30 ° C, the temperature is below 18 ° C, and the cell counting accuracy is reduced. Inspection process Blood is drawn and detected by a professional inspection instrument, often expressed by the coefficient of variation (CV%) of the measured red blood cell volume. Not suitable for the crowd Have a coagulopathy such as hemophilia. Adverse reactions and risks Dizziness or fainting: When blood is drawn, due to emotional overstress, fear, reflex caused by vagus nerve excitability, blood pressure drop, etc., the blood supply to the brain is insufficient to cause fainting or dizziness.

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