red blood cell deformability

Normal red blood cells are shaped like a double concave disk. In the microcirculation, RBC can be further transformed into a bullet shape, a parachute shape, or a slipper shape. Therefore, RBC can change itself according to the flow field condition and the blood vessel group. The shape, which is the deformability of RBC, RBC deformability is the ability to describe the shape change of RBC in the flow, so it is also called the deformation ability of RBC. If you discuss it from another angle (that is, the degree to which the shape of the RBC is not easily changed), the term "rigidity of red blood cells" can also be used. Red blood cells are important gas exchange units in the body, and transport oxygen and nutrients to various tissues and organs, while transporting waste away. The variability of red blood cells is necessary for the blood to complete this physiological function, which directly affects To the blood circulation. When red blood cells flow in the blood, maintaining good deformability is essential for maintaining normal flow in the blood vessels, ensuring normal perfusion of the microcirculation, and supplying organs, tissue oxygen and nutrients, and also helping to maintain the normal life of red blood cells. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: not fasting Tips: Listen to the doctor and put your posture. Normal value (1) Viscosity detection method. 1 Rotary viscometer detection method 180s-1 < 1.00. 2 capillary viscometer detection method 3.07 ~ 3.95. (2) Microporous membrane method. 1 whole blood filtration method 0.19 ~ 0.39. 2 red blood cell suspension filtration method 0.90 ~ 1.06. Clinical significance Increased red blood cell deformability decreased, blood flow decreased, see hypertension, coronary heart disease, stroke, hyperlipidemia, diabetes, pulmonary heart disease, liver disease, peripheral vascular disease, acute myocardial infarction, shock, burns and certain blood diseases. High results may be diseases: coronary heart disease considerations Before the inspection: no special contraindications. Listen to the doctor and put your posture. Inspection process Inspection methods: There are many methods for determining the deformability of red blood cells. In principle, they can be divided into two categories. One is to subject the blood samples to a large geometric scale measurement system to undergo shear stress, and to determine the average of red blood cells in the flow. Deformable properties such as viscosity measurement calculations and laser diffraction methods. Another method is to use a narrow channel system to pass red blood cells one by one, such as micropipette method and filtration method, the former can determine the deformability of a single red blood cell, and the latter reflects the deformation performance of a group of red blood cells. Not suitable for the crowd Hemophilia and diffuse intravascular coagulation. Adverse reactions and risks Infection: Do not touch the dirt after blood collection. Do not wash your hands immediately to avoid infection.

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