Anti-Hepatitis E Virus Antibody

Hepatitis EV (hepatitisEVirus, HEV) is a pathogen of hepatitis E caused by intestinal transmission. It is spherical, has no cyst on the surface, is stereotacticly icosahedral, has a protruding structure on the surface, and the internal nucleic acid is single-stranded RNA. Hepatic RNA virus genus of the genus Vibrio. HEV has the surface antigen HEVAg, which stimulates the body to produce antibodies. Basic Information Specialist classification: Infectious disease examination and classification: liver function examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Normal when negative. Positive: Positive with hepatitis E virus. Tips: Patients pay attention to normal diet and check with doctors. Normal value A value <0.3, negative. Clinical significance Abnormal result The levels of ORF2 antibody and ORF3 antibody were higher in the early stage of onset, and both decreased with the prolongation of the disease course. ORF3 antibody was particularly obvious. Combined detection of ORF2 and ORF3 antibodies increases the sensitivity of the assay. Serum anti-HEVIgM and anti-HEV IgG positive rates were 71.1% (32/45) and 97.8% (44/45) in the first half of the onset, and the anti-HEVIgM was earlier than the course of the disease. Need to check the crowd: patients with hepatitis. Positive results may be diseases: Children with hepatitis E virus, hepatitis E virus considerations Attention during the examination: the patient pays attention to the normal diet and cooperates with the doctor. Requirements for inspection: (1) Strictly follow the operating procedures. (2) Quality control blank hole A value < 0.2, negative control A value > 0 and < 0.2 (minus blank), positive control A value > 0.8 (minus blank). (3) The unused coated sheets are placed in a sealed bag containing desiccant and stored in a sealed container. (4) Do not keep warm in a water bath after adding samples and reagents. (5) Do not place the substrate and substrate solution under strong light, and take the OPD sheet with a non-metallic tweezers. (6) Others are the same as the ELISA method. Inspection process A total of 32,600 adult clinical test samples were collected from non-popular years. Anti-HAVIgM was detected by enzyme immunoassay (EIA) capture antibody method, and anti-HEVIgM was detected by EIA indirect method. RESULTS: Of the 32,600 samples, 1785 were anti-HAVIgM, 34 were positive, the positive rate was 1.9, and 1820 were anti-HEVIgM, 88 were positive, and the positive rate was 4.84. Not suitable for the crowd Generally there are no people who are not suitable. Adverse reactions and risks Generally no adverse reactions.

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