Tensilon test
Tengxilong hydrochloride is a short-acting cholinesterase inhibitor. It is best to use the double-blind method when doing the Teng Xilong test. Common side effects of bradycardia, hypotension, tearing, flushing, gastrointestinal fistula, etc., often transient. If you need to use atropine to fight. Basic Information Specialist classification: growth and development check classification: physical examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: If the cholinergic crisis is temporarily aggravated with fasciculation, ruminant crisis. negative: normal. Positive: Can be diagnosed as myasthenia gravis. Tips: Inappropriate people have some muscle weakness when they are tired, and there are no patients with weakness in the temporary examination. Normal value Symptoms did not resolve after the injection of Tengxilong. Clinical significance Abnormal results: Increased strength after intravenous injection of Teng Xilong is a strong criterion for post-synaptic neuromuscular transmission, especially for the diagnosis of myasthenia gravis, but it is also reported positively in many other diseases. 1. Myasthenia gravis (Myastheniagravis) Sensitivity was estimated to be 86% in the MG eye muscle type and 95% in the systemic type. Specificity is difficult to assess, but may be higher in systemic type. 2. Other neuromuscular transmission disorders positive for Teng Xilong Eaton-Lambert syndrome, botulism, congenital muscle weakness, snake bite poisoning. 3. Motor neuron disease 4. Other Guillain-Barre syndrome, brain stem glioma, multiple sclerosis, pituitary tumor, aneurysm compression. People who need to be examined: patients with myasthenia gravis. Positive results may be diseases: pediatric myasthenia gravis, myasthenia gravis syndrome considerations Pre-examination contraindications: Before the test, the muscles of specific brain innervation muscles such as the levator palpebrae and extraocular muscles should be evaluated. The muscle strength of the limbs should be measured (using the grip force tester). Severe patients should be checked for vital capacity. Requirements for inspection: Actively cooperate with the doctor's work. Inspection process Tengxilong 10mg was diluted to 1ml and intravenously injected with 2mg (0.2ml). If there was no adverse reaction and no increase in muscle strength after 45 s, the remaining 8 mg (0.8 ml) was slowly injected for about 1 min. Side effects include: mild muscarinic effects such as nausea, vomiting, increased peristalsis, hyperhidrosis, and convulsions. The results can be determined by subcutaneous injection of atropine 0.8mg in advance: most patients have symptoms after 5mg injection. In the case of myasthenia gravis, the respiratory muscle weakness improves within 30 to 60 s, and the symptoms are relieved, lasting only 4 to 5 minutes. If the cholinergic crisis is temporarily aggravated with fasciculation, ruminant crisis. Non-response determination Tengxilong test positive should include objective muscle contractility, enhanced sag and diplopia, etc. significantly reduced or disappeared. Not suitable for the crowd There are some muscle weaknesses in fatigue, and there are no patients with weakness in the temporary examination. Adverse reactions and risks Generally no adverse reactions.
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