Vitamin B3 (VitB3, VB3)

Vitamin B3 (VB3, pantothenic acid) is a water-soluble vitamin B vitamin. Participates in the metabolism of transacylase, the main function involved in the synthesis of hemoglobin and steroids. Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reduced in anemia, adrenal insufficiency, dermatitis. Normal value: Vitamin B3 (free): 0.09-0.36μmol/L Vitamin B3 (total): 1.74 - 2.49 μmol / L Above normal: Rare. negative: Positive: Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value Free 0.09 to 0.36 μmol/L (20 to 80 ng/ml). The total amount is 1.74 to 2.49 μmol/L (382 to 546 ng/ml). Clinical significance 1, reduced in anemia, adrenal insufficiency, dermatitis. 2, niacin deficiency can cause ecdysis. Prodromal symptoms: weight loss, fatigue, poor memory, insomnia, etc., if not treated in time, dermatitis, diarrhea and dementia may occur. Skin Symptoms: Typical symptoms are common in exposed parts of the body, such as symmetrical dermatitis on the back of the hand, wrist, forearm, face, neck, back of the foot, and ankle. Digestive system symptoms: mainly keratitis, glossitis, diarrhea, etc., diarrhea is a typical symptom of this disease, early suffering from constipation, followed by digestive gland atrophy and enteritis often have diarrhea, the number of times. Symptoms of the nervous system: rarely appear in the early stages, and appear when the symptoms of the skin and digestive system are obvious. Mild patients may have generalized weakness, irritability, depression, forgetfulness and insomnia. In severe cases, there are arrogance, auditory hallucinations, unconsciousness, stupor, and even dementia. Low results may be diseases: adrenal insufficiency, anemia considerations Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, saving you time. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process Immediately after venous blood collection, the test was performed by ELISA. Serum is used to detect, first the blood is agglutinated for at least half an hour, and then serum is taken. After diluting the enzyme complex with the diluent, add serum and a negative, positive control, and a control (this is a strict requirement, and its range must be within the control range). After an hour of incubation, then wash the plate, add the substrate, half an hour to avoid the light reaction and add the stop solution to complete the reaction part, then the reading. The result is judged to be negative or positive by the value. Not suitable for the crowd Inappropriate people: generally no special population. Those without examination indications should not be tested. Adverse reactions and risks 1. Niacin deficiency can progress to insanity, disorientation, seizures, tension schizophrenia, hallucinations, confusion, paralysis, and even death. 2, peripheral neuritis symptoms such as limb numbness, burning sensation, gastrocnemius tenderness and abnormal reflection can occur. 3, sometimes subacute spinal cord posterior column combined degeneration symptoms, may be related to other vitamin B deficiency.

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