Vitamin B2 (VitB2, VB2)

Vitamin B2 is a water-soluble vitamin. The vitamin B2 required by the human body mainly depends on the supply of food. The milk and eggs are rich in vitamin B2, and also in green vegetables, but the vitamin B2 content of plant foods is not high. In the absence of vitamin B2, the activity of many enzymes decreases, and the rate of oxidation in mitochondria decreases, directly affecting energy metabolism. Therefore, it is a vitamin necessary to maintain the normal growth of the body. Vitamin B2 is one of the 13 essential vitamins in the body. As a member of the vitamin B family, it is slightly soluble in water, soluble in sodium chloride solution, and easily soluble in dilute sodium hydroxide solution. Basic Information Specialist classification: inspection classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not overeating before the inspection, follow the doctor's instructions. Normal value The reference range for ACEGR is <1.2, if >1.4 is diagnostic. Clinical significance Abnormal result Vitamin B2 deficiency is a common nutritional deficiency disease. Because vitamin B2 is a necessary factor for maintaining normal growth of the human body, the lack of vitamin B2 in the body has a great influence on the physiological functions of the human body, and the scope is wide. It is common that the oral cavity and the skin are abnormal, and a serious deficiency can lead to growth stoppage. Most of the disease is caused by insufficient supply of vitamin B2 in the diet or excessive utilization or malabsorption. Therefore, according to the history of vitamin B2 deficiency in the diet and scrotal skin lesions, oral symptoms, seborrheic dermatitis, a preliminary clinical diagnosis is made, and then treated with vitamin B2. Low results may be diseases: riboflavin deficiency, vulvar skin seborrheic dermatitis, seborrheic dermatitis, oral ulcers, map tongue, keratitis considerations Contraindications before the examination: It is not advisable to overeating before the examination, and it is necessary to follow the doctor's instructions. Requirements for examination: The urine volume of children is not easy to collect and can be collected multiple times. Inspection process Evaluation of laboratory diagnostic methods: 1, ACEGR as a specific diagnostic indicator of human vitamin B2 deficiency can be preferred. The method has the advantages of less blood volume, high sensitivity, stable method, and the like, and can directly reflect the metabolism of the body flavin. 2, although the 24h urine vitamin B2 determination can correctly identify the amount of vitamin B2 excreted in the urine one day, but the urine volume is not easy to collect, especially in children. The amount of vitamin B2 excreted in the urine of 1 hour in the fasting can be measured, and the measured value is converted into the discharge amount of 24 hours. Not suitable for the crowd Need to check the population for vitamin B2 deficiency groups. No deficiency is generally not required for testing. Adverse reactions and risks Excessive intake of vitamin B2 may cause itching, paralysis, nosebleeds, burning sensation, and stinging. If you are taking anticancer drugs, such as methotrexate, excessive B2 will reduce the effectiveness of these anticancer agents.

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