Serum Anion Determination

The serum anion measurement measures the concentration of the main anion Cl- in the serum to determine the ion state in the body. Cl- is the main anion in the extracellular fluid of the human body and plays an important role in regulating the body's acid-base balance, osmotic pressure and water distribution. Loss of bicarbonate, often relative to Cl-, leading to high chloride acidosis, such as type II renal tubular acidosis; or when entering a drug containing high Cl-, such as the input of arginine hydrochloride, a large amount of Ammonium chloride can cause an increase in serum chlorine. Basic Information Specialist classification: Respiratory examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: 1, frequent vomiting and gastrointestinal decompression, loss of a large amount of gastric juice, so that serum chloride ions are reduced. 2, acute renal insufficiency, often hypochloremia, which is due to urea retention affects plasma osmotic pressure, plasma NaCl decreased, in order to regulate the changes in osmotic pressure. 3, adrenal hyperfunction, such as Cushing syndrome, can show low potassium and low chloride alkalosis. 4, chronic respiratory insufficiency, such as pulmonary acidosis caused by respiratory acidosis, due to CO2 retention, plasma [HCO3-] corresponding increase, Cl- increased from renal excretion, serum Cl- decreased. 5, cardiac dysfunction, cirrhosis ascites, inappropriately restrict salt and the use of intravenous diuretics. For example, furosemide can cause Cl- to be lost, resulting in a decrease in serum Cl-. Normal value: Serum chloride: 98-106mmol/L Above normal: 1, acute glomerulonephritis and chronic glomerulonephritis, there is Cl- retention, it is often with Na + at the same time. 2, loss of bicarbonate, often relative to the increase of Cl-, leading to high chloride acidosis, such as type II renal tubular acidosis; or input of drugs containing high Cl-, such as the input of arginine hydrochloride, A large amount of ammonium chloride can cause an increase in serum chlorine. negative: Positive: Tips: Before taboo: Avoid taking oxidizing drugs. Normal value 98 to 106 mmol/L (98 to 106 mEq/L). Clinical significance Abnormal result Chloride ion increase: 1, acute glomerulonephritis and chronic glomerulonephritis, there is Cl- retention, it is often with Na + at the same time. 2, loss of bicarbonate, often relative to the increase of Cl-, leading to high chloride acidosis, such as type II renal tubular acidosis; or input of drugs containing high Cl-, such as the input of arginine hydrochloride, A large amount of ammonium chloride can cause an increase in serum chlorine. Chloride reduction: 1, frequent vomiting and gastrointestinal decompression, loss of a large amount of gastric juice, so that serum chloride ions are reduced. 2, acute renal insufficiency, often hypochloremia, which is due to urea retention affects plasma osmotic pressure, plasma NaCl decreased, in order to regulate the changes in osmotic pressure. 3, adrenal hyperfunction, such as Cushing syndrome, can show low potassium and low chloride alkalosis. 4, chronic respiratory insufficiency, such as pulmonary acidosis caused by respiratory acidosis, due to CO2 retention, plasma [HCO3-] corresponding increase, Cl- increased from renal excretion, serum Cl- decreased. 5, cardiac dysfunction, cirrhosis ascites, inappropriately restrict salt and the use of intravenous diuretics. For example, furosemide can cause Cl- to be lost, resulting in a decrease in serum Cl-. Need to check the population of patients with renal insufficiency, people with frequent vomiting. Low results may be diseases: high results of acute gastroenteritis may be diseases: chronic glomerulonephritis, acute glomerulonephritis precautions Inappropriate crowd: no Contraindications before examination: Avoid taking oxidizing drugs. Pay attention to rest and keep an empty stomach. Requirements for inspection: No special requirements. Inspection process The peripheral blood mainly has ear lobe blood and fingertips to take blood. The baby can take blood from the heel. The earlobe has a lighter blood pressure, but the blood volume is less, especially those with smaller earlobes are more difficult to take blood. The blood pressure of the fingertips is more obvious, but the blood collection is more, especially for the blood routine test, the stable measurement results can be obtained. The skin should be cleaned before blood collection. Do not take blood immediately after entering the room in the cold outdoor winter. After the body is warm, especially the ear drops and hands should be warmed up. Do not use hot water to heat your hands before taking blood. Keep your fingers dry. If your fingertips have wounds, paronychia, redness or skin disease, avoid using this finger. Fingertip blood collection generally uses the ring finger, because the ring finger will not affect the daily function of the hand after piercing, of course, the middle finger or index finger can also be used, no special difference. When collecting blood in the ear, remove the earrings and other hanging ornaments on the earlobe. Do not hang up immediately after blood collection. After blood collection, apply sterile cotton blocks or other disinfecting hemostatic articles to pinch the needle and puncture the area. Do not touch the dirt. Do not wash your hands immediately. Serum was separated and the anion concentration was measured. Not suitable for the crowd no. Adverse reactions and risks no.

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