Serum α1-microglobulin
α1MG is a low molecular weight glycoprotein, a hydrophobic ligand binding protein, and is also a member of the Lipocatin superfamily. It is synthesized by liver and lymphocytes and is widely found on the surface of body fluids and lymphocyte membranes. There are two forms of α1 microglobulin in the blood, one is free form, and the other is a form that binds to IgA. The free form is easily filtered by the glomerulus, but almost all of it is reabsorbed and metabolized by the renal tubules, and the binding type is not easily filtered. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Severe liver function damage. Normal value: Serum α1-microglobulin (RIA method): 0.01-0.03g/L Above normal: Renal insufficiency, IgA myeloma, liver cancer, etc. negative: Positive: Tips: fasting blood test, fasting 8-12 hours before the test. Normal value The RIA method (radioimmunoassay) is 0.01 to 0.03 g/L (10 to 30 mg/L). Clinical significance 1. Elevation: renal insufficiency, IgA myeloma, liver cancer, etc. 2, lower: severe liver function damage. Low results may be diseases: high renal insufficiency may result in diseases: cirrhosis precautions The α1-microglobulin assay can be used as an early sensitive indicator of renal damage. Inspection process As determined by the RIA method (radioimmunoassay). Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally no complications and harm.
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