renal tubular ammonia hippuric acid maximum excretion test

After PAH injection, no catabolism was performed. About 20% was filtered from the glomerulus in the original shape, 80% was excreted by the proximal tubule, and was not reabsorbed by the renal tubule. The excretion increased with the increase of plasma PAH level. When the plasma concentration increases to a certain limit (about 600mg/L), the renal tubules have reached the maximum amount of excretion. Even if the plasma concentration of PAH is increased, the amount of urine excreted will not increase any more. For maximum excretion of ammonia hippuric acid. The maximum excretion minus the glomerular filtration excess (measured by the inulin clearance rate), ie TmPAH, can be used as an indicator for detecting the number and quality of renal tubules, and is one of the methods for determining the active excretion function of proximal tubules. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Mild reduction is seen in mild acute glomerulonephritis and heart failure. Moderate reduction is seen in hypertension, renal arteriosclerosis, and pyelonephritis. Significant reduction in chronic glomerulonephritis, acute nephritis, chronic pyelonephritis and interstitial nephritis. Normal value: Maximum excretion of renal tubular aminopurine: 60-90mg/(min·1.73m2) Above normal: No clinical significance. negative: Positive: Tips: Please cooperate with the doctor when checking. Normal value 60 to 90 mg / (min · 1.73 m 2 ). Clinical significance Mild reduction is seen in mild acute glomerulonephritis and heart failure. Moderate reduction is seen in hypertension, renal arteriosclerosis, and pyelonephritis. Significant reduction in chronic glomerulonephritis, acute nephritis, chronic pyelonephritis and interstitial nephritis. Low results may be diseases: glomerulonephritis, chronic pyelonephritis, interstitial nephritis precautions The substances used for the measurement of blood flow are p-aminopuric acid, sulphuric acid and phenol red. Among them, aminoacetic acid is most commonly used. Inspection process Urine specimens are diluted with water from 1/200 to 1/1000. Whether the plasma or urine is diluted, the amount of PAH in the diluent should be between 2.3 and 20 μmol/L. Label the measuring tube (U), standard tube (S), blank tube (B), and then follow the steps. Not suitable for the crowd Menstrual women. Adverse reactions and risks no.

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