Congenital giant cell inclusion disease

Congenital giant cell inclusion body infection is a congenital systemic infection syndrome infection caused by the infection of human cytomegalovirus (CMV). Due to the size of infected cells, inclusion bodies appear in the nucleus and cytoplasm. The disease is also called cytomegalic inclusion disease. There are two types, one is salivary adenoviral disease, which is an asymptomatic localized infection, and most of them remain as a dominant or chronic infection of the salivary glands and remain for a long time. The other is a systemic disease, which is relatively rare and mainly invades small infants. It is characterized by the discovery of large cells containing nuclear and cytoplasmic inclusions in many organs and tissues, accompanied by systemic symptoms, caused by intrauterine virus infection. One of the important causes of fetal malformations.

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