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Cretin disease is caused by hypothyroidism. Due to congenital lack of thyroid gland or severe insufficiency of thyroid function, the body will experience a series of metabolic disorders, which will cause the development of bones, muscles and the central nervous system. The patient's mental retardation, mental development is slow, and the skin has a doughy edema, that is, myxedema. Due to the delayed ossification process, the body is abnormally short.

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