Pediatric carbon monoxide poisoning

I. Overview: Carbon monoxide is a colorless, odorless, non-irritating gas. Carbon monoxide poisoning is mostly caused by leaking gas pipes, malfunctioning gas switches and operating errors, and no ventilation equipment in the room, or using gas water heaters to bathe and synthesize ammonia, coking, steel smelting, and domestic coal stove heating, poor ventilation or improper protection . After inhaling carbon monoxide, it enters the blood circulation through the alveoli and mainly forms oxyhemoglobin (HbCO) with hemoglobin. Because the affinity of CO and Hb is 240 times greater than that of O2 and Hb, the blood's oxygen carrying capacity decreases; once HbCO is formed, its dissociation is slower than oxidized hemoglobin (HbO2) (only 1/3600), and HbCO's The presence also affects the dissociation of HbO2, hinders the release and transmission of oxygen, leads to hypoxemia, causes tissue hypoxia, and severely causes death.

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