Central pontine myelin lysis

Central pontine myelinolysis (CPM) is a lethal disease characterized by symmetrical demyelination at the base of the pontine. This disease is a rare acute myelin-soluble disease. It is now thought that it is due to hyponatremia, specifically due to the excessively rapid correction of hyponatremia. Adams et al. (1959) first reported. The first case of Adams et al. In 1950 observed a young chronic alcoholic patient who was hospitalized with symptoms of alcohol withdrawal, developed within a few days into quadriplegia and pseudobulbar palsy, and died quickly. The main finding of the pathological examination was a large area of ​​symmetric demyelinating lesions at the base of the pontine, hence its name.

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