Drug-induced lung disease

Drugs play an extremely important role in the prevention, treatment and diagnosis of diseases, but on the other hand, they can cause damage to various organs of the body due to their toxic and side effects. Although it was observed by William Osler as early as 1880 that excessive morphine could cause acute pulmonary edema, it was not until 1972 that Rosenow systematically discussed 20 drugs that are definitely related to lung injury. Since then, more and more reports about drugs and lung diseases have been paid more and more attention. To date, more than 100 drugs have been reported to cause lung disease. Adverse drug reactions to the lung are part of systemic adverse drug reactions and their clinical manifestations vary. Some are acutely ill and severe, while others are subacute or chronic. The pathophysiological changes caused by some drugs are temporary and reversible. They can disappear after stopping the drug, while others can cause permanent damage to the lung tissue, and even severely endanger life. This kind of drug-induced lung disease is called drug-induced lung diseases (DILD).

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